Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNIH2
  • Mouse genes Cnih2
  • Rat genes Cnih2
  • Zfish genes cnih2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnih2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CNIH2	IPI	UniProtKB:P42261	Human	PMID:20805473
Molecular Function	GO:0005515	protein binding	CNIH2	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNIH2	IPI	UniProtKB:P19397	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNIH2	IPI	UniProtKB:P31937	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNIH2	IPI	UniProtKB:Q5T7V8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNIH2	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNIH2	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cnih2	IPI	UniProtKB:P19490	Rat	PMID:20805473|RGD:8553646
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Cnih2	IDA		Rat	PMID:19265014|RGD:8554136
Cellular Component	GO:0030425	dendrite	Cnih2	IDA		Mouse	MGI:MGI:4879039|PMID:21172611
Cellular Component	GO:0043198	dendritic shaft	Cnih2	IDA		Rat	PMID:19265014|RGD:8554136
Cellular Component	GO:0043197	dendritic spine	Cnih2	IDA		Mouse	MGI:MGI:4879039|PMID:21172611
Cellular Component	GO:0098978	glutamatergic synapse	Cnih2	IDA		Rat	PMID:21172611|RGD:8554236
Cellular Component	GO:0098978	glutamatergic synapse	Cnih2	IDA		Rat	PMID:24853943|RGD:13702348
Cellular Component	GO:0098978	glutamatergic synapse	Cnih2	IMP		Rat	PMID:24853943|RGD:13702348
Cellular Component	GO:0014069	postsynaptic density	Cnih2	IDA		Mouse	MGI:MGI:4879039|PMID:21172611
Cellular Component	GO:0098839	postsynaptic density membrane	Cnih2	IDA		Rat	PMID:21172611|RGD:8554236
Cellular Component	GO:0045211	postsynaptic membrane	Cnih2	IDA		Rat	PMID:19265014|RGD:8554136
Biological Process	GO:0051668	localization within membrane	Cnih2	IDA		Rat	PMID:19265014|RGD:8554136
Biological Process	GO:1903743	negative regulation of anterograde synaptic vesicle transport	Cnih2	IMP		Rat	PMID:24094107|RGD:10400859
Biological Process	GO:1902684	negative regulation of receptor localization to synapse	Cnih2	IMP		Rat	PMID:24094107|RGD:10400859
Biological Process	GO:2000311	regulation of AMPA receptor activity	CNIH2	IDA		Human	PMID:20805473
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cnih2	IDA		Mouse	MGI:MGI:4879039|PMID:21172611
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cnih2	IDA		Rat	PMID:19265014|RGD:8554136
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cnih2	IDA		Rat	PMID:20805473|RGD:8553646
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cnih2	IMP		Rat	PMID:24094107|RGD:10400859
Biological Process	GO:0042391	regulation of membrane potential	Cnih2	IDA		Rat	PMID:19265014|RGD:8554136
Biological Process	GO:2000310	regulation of NMDA receptor activity	Cnih2	IMP		Rat	PMID:24094107|RGD:10400859
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Cnih2	IDA		Rat	PMID:24853943|RGD:13702348
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Cnih2	IMP		Rat	PMID:24853943|RGD:13702348
Biological Process	GO:0035249	synaptic transmission, glutamatergic	Cnih2	IDA		Rat	PMID:19265014|RGD:8554136

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern