Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLPP
  • Mouse genes Clpp
  • Rat genes Clpp
  • Zfish genes clpp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clpp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	CLPP	IDA		Human	PMID:22354088
Molecular Function	GO:0042802	identical protein binding	Clpp	IPI	RGD:1588583	Rat	PMID:16115876|RGD:2302219
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:O76031	Human	PMID:11923310
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:O76031	Human	PMID:16115876
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P28799	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P61970	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P67775	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q12805	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q7Z4N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q93062-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q9NRQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q9NWQ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q9NYB9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q9Y5L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q8TB36	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLPP	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Clpp	IPI	PR:Q9JHS4	Mouse	PMID:10347188
Molecular Function	GO:0005515	protein binding	Clpp	IPI	RGD:1312578	Rat	PMID:16115876|RGD:2302219
Molecular Function	GO:0004252	serine-type endopeptidase activity	CLPP	IDA		Human	PMID:11923310
Cellular Component	GO:0009368	endopeptidase Clp complex	CLPP	IPI		Human	PMID:15522782
Cellular Component	GO:0009368	endopeptidase Clp complex	CLPP	IDA		Human	PMID:11923310
Cellular Component	GO:0005759	mitochondrial matrix	CLPP	IDA		Human	PMID:10525407
Cellular Component	GO:0005739	mitochondrion	CLPP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	CLPP	IDA		Human	PMID:22354088
Cellular Component	GO:0005739	mitochondrion	Clpp	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Clpp	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Clpp	IDA		Mouse	PMID:10754102
Cellular Component	GO:0005739	mitochondrion	Clpp	IDA		Rat	PMID:16115876|RGD:2302219
Biological Process	GO:0033619	membrane protein proteolysis	CLPP	IDA		Human	PMID:22354088
Biological Process	GO:0006508	proteolysis	CLPP	IDA		Human	PMID:15522782
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	CLPP	IDA		Human	PMID:11923310

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern