Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLEC4A
  • Mouse genes Clec4a4
  • Rat genes Clec4a,Clec4a2
  • Zfish genes lectin,si:ch211-125e6.12,si:ch211-125e6.13
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clec4a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	CLEC4A	IDA		Human	PMID:27015765
Molecular Function	GO:0030246	carbohydrate binding	CLEC4A	IDA		Human	PMID:27015765
Molecular Function	GO:0097367	carbohydrate derivative binding	Clec4a4	IDA		Mouse	PMID:24108122
Molecular Function	GO:0005537	mannose binding	CLEC4A	IDA		Human	PMID:27015765
Biological Process	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	CLEC4A	IDA		Human	PMID:20530286
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	CLEC4A	IDA		Human	PMID:20530286
Biological Process	GO:0001818	negative regulation of cytokine production	CLEC4A	IDA		Human	PMID:18258799
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	CLEC4A	IDA		Human	PMID:18258799
Biological Process	GO:0002470	plasmacytoid dendritic cell antigen processing and presentation	CLEC4A	IDA		Human	PMID:18258799
Biological Process	GO:0002470	plasmacytoid dendritic cell antigen processing and presentation	CLEC4A	IDA		Human	PMID:20530286

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern