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Gene Ontology Browser
Term Detail
GO term:antigen processing and presentation of exogenous peptide antigen via MHC class I
Synonym: antigen presentation, exogenous antigen via major histocompatibility complex class I
Synonym: antigen presentation, exogenous antigen via MHC class I
Synonym: cross presentation
Synonym: cross-presentation
Synonym: cross priming
Synonym: cross-priming
Synonym: exogenous peptide antigen processing and presentation via MHC class I
GO id:GO:0042590
Definition:The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of exogenous antigen
                                        is-aantigen processing and presentation of exogenous peptide antigen
                                                is-aantigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] (6 genes, 6 annotations)
                                                        is-aantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
                                                        is-aantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
                                                is-aantigen processing and presentation of exogenous peptide antigen via MHC class Ib +
                                                is-aantigen processing and presentation of exogenous peptide antigen via MHC class II


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of peptide antigen
                                        is-aantigen processing and presentation of exogenous peptide antigen
                                                is-aantigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] (6 genes, 6 annotations)
                                                        is-aantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
                                                        is-aantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
                                                is-aantigen processing and presentation of exogenous peptide antigen via MHC class Ib +
                                                is-aantigen processing and presentation of exogenous peptide antigen via MHC class II


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of peptide antigen
                                        is-aantigen processing and presentation of peptide antigen via MHC class I
                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class I +
                                                is-aantigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] (6 genes, 6 annotations)
                                                        is-aantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
                                                        is-aantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
                                                negatively-regulatesnegative regulation of antigen processing and presentation of peptide antigen via MHC class I +
                                                part-ofpeptide antigen assembly with MHC class I protein complex
                                                positively-regulatespositive regulation of antigen processing and presentation of peptide antigen via MHC class I
                                                regulatesregulation of antigen processing and presentation of peptide antigen via MHC class I +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory