Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLDN2
  • Mouse genes Cldn2
  • Rat genes Cldn2
  • Zfish genes cldn2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cldn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Cldn2	IPI	UniProtKB:O88552	Mouse	MGI:MGI:3513972|PMID:10562289
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:O00501	Human	PMID:25323998
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:O95832	Human	PMID:25323998
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:A2RU14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:O43561-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:P24593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:P54852	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:P60201-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:P78410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q07325	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q08AM2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q14416	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q6UWB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q8N6G5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q9UBY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q9UHP7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN2	IPI	UniProtKB:Q9Y6I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cldn2	IPI	UniProtKB:P39447|UniProtKB:Q9QXY1|UniProtKB:Q9Z0U1	Mouse	MGI:MGI:1350677|PMID:10601346
Molecular Function	GO:0005515	protein binding	Cldn2	IPI	UniProtKB:Q9Z0G9	Mouse	MGI:MGI:3513972|PMID:10562289
Cellular Component	GO:0005923	bicellular tight junction	Cldn2	IMP		Mouse	MGI:MGI:6780303|PMID:32149733
Cellular Component	GO:0005923	bicellular tight junction	Cldn2	IDA		Mouse	MGI:MGI:1274767|PMID:9647647
Cellular Component	GO:0005923	bicellular tight junction	Cldn2	IDA		Mouse	PMID:16520537
Cellular Component	GO:0005923	bicellular tight junction	Cldn2	IDA		Mouse	PMID:22275141
Cellular Component	GO:0005911	cell-cell junction	CLDN2	IDA		Human	PMID:21415414
Biological Process	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	Cldn2	IDA		Mouse	MGI:MGI:3687671|PMID:10508613
Biological Process	GO:0098609	cell-cell adhesion	Cldn2	IMP		Mouse	MGI:MGI:6780303|PMID:32149733

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern