Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLASP2
  • Mouse genes Clasp2
  • Rat genes Clasp2
  • Zfish genes clasp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clasp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002162	dystroglycan binding	CLASP2	IPI	UniProtKB:Q14118	Human	PMID:23940118
Molecular Function	GO:0008017	microtubule binding	CLASP2	IDA		Human	PMID:26003921
Molecular Function	GO:0008017	microtubule binding	Clasp2	IDA		Mouse	PMID:11290329
Molecular Function	GO:0008017	microtubule binding	Clasp2	IDA		Rat	PMID:11290329|RGD:68300
Molecular Function	GO:0051010	microtubule plus-end binding	CLASP2	IDA		Human	PMID:11290329
Molecular Function	GO:0051010	microtubule plus-end binding	CLASP2	IDA		Human	PMID:19632184
Molecular Function	GO:0005515	protein binding	CLASP2	IPI	UniProtKB:O55156	Human	PMID:11290329
Molecular Function	GO:0005515	protein binding	CLASP2	IPI	UniProtKB:Q8IWJ2	Human	PMID:17543864
Molecular Function	GO:0005515	protein binding	CLASP2	IPI	UniProtKB:Q15691	Human	PMID:19632184
Molecular Function	GO:0005515	protein binding	CLASP2	IPI	UniProtKB:Q15691	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CLASP2	IPI	UniProtKB:Q15691	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	Clasp2	IPI	UniProtKB:Q9QXZ0	Mouse	MGI:MGI:3828223|PMID:18854161
Molecular Function	GO:0005515	protein binding	Clasp2	IPI	UniProtKB:Q3U5C7	Mouse	PMID:27378169
Molecular Function	GO:0005515	protein binding	Clasp2	IPI	PR:Q5SNZ0	Mouse	PMID:24211587
Molecular Function	GO:0005515	protein binding	Clasp2	IPI	PR:Q9Z0H8	Mouse	PMID:11290329
Molecular Function	GO:0005515	protein binding	Clasp2	IPI	PR:Q922J3	Mouse	PMID:11290329
Cellular Component	GO:0045180	basal cortex	CLASP2	IDA		Human	PMID:23940118
Cellular Component	GO:0005938	cell cortex	CLASP2	IDA		Human	PMID:17113391
Cellular Component	GO:0031252	cell leading edge	CLASP2	IDA		Human	PMID:24859005
Cellular Component	GO:0031252	cell leading edge	Clasp2	IDA		Mouse	PMID:24211587
Cellular Component	GO:0005881	cytoplasmic microtubule	CLASP2	IDA		Human	PMID:11290329
Cellular Component	GO:0005829	cytosol	CLASP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	CLASP2	IDA		Human	PMID:24859005
Cellular Component	GO:0005794	Golgi apparatus	CLASP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	CLASP2	IDA		Human	PMID:11290329
Cellular Component	GO:0005794	Golgi apparatus	Clasp2	IDA		Mouse	PMID:11290329
Cellular Component	GO:0000776	kinetochore	CLASP2	IMP		Human	PMID:16866869
Cellular Component	GO:0016020	membrane	CLASP2	HDA		Human	PMID:19946888
Cellular Component	GO:0005874	microtubule	CLASP2	IDA		Human	PMID:24859005
Cellular Component	GO:0005874	microtubule	CLASP2	IDA		Human	PMID:17543864
Cellular Component	GO:0005874	microtubule	CLASP2	IDA		Human	PMID:20937854
Cellular Component	GO:0005874	microtubule	Clasp2	IDA		Rat	PMID:11290329|RGD:68300
Cellular Component	GO:0015630	microtubule cytoskeleton	Clasp2	IDA		Mouse	PMID:17113391
Cellular Component	GO:0015630	microtubule cytoskeleton	Clasp2	IDA		Mouse	PMID:11290329
Cellular Component	GO:0072686	mitotic spindle	CLASP2	IMP		Human	PMID:16866869
Cellular Component	GO:0005886	plasma membrane	CLASP2	IDA		Human	PMID:20937854
Cellular Component	GO:0032587	ruffle membrane	CLASP2	IDA		Human	PMID:20937854
Cellular Component	GO:0032587	ruffle membrane	Clasp2	IDA		Rat	PMID:22992739|RGD:28912745
Cellular Component	GO:0005802	trans-Golgi network	CLASP2	IDA		Human	PMID:17543864
Biological Process	GO:0016477	cell migration	Clasp2	IGI	MGI:MGI:1916034	Mouse	PMID:27378169
Biological Process	GO:0032869	cellular response to insulin stimulus	Clasp2	IEP		Rat	PMID:22992739|RGD:28912745
Biological Process	GO:0030010	establishment of cell polarity	Clasp2	IGI	MGI:MGI:1916034	Mouse	PMID:27378169
Biological Process	GO:0007163	establishment or maintenance of cell polarity	Clasp2	IMP	MGI:MGI:3693618	Mouse	PMID:17113391
Biological Process	GO:0010458	exit from mitosis	CLASP2	IMP		Human	PMID:16866869
Biological Process	GO:0010761	fibroblast migration	Clasp2	IMP	MGI:MGI:3693618	Mouse	PMID:17113391
Biological Process	GO:0007030	Golgi organization	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:0034453	microtubule anchoring	CLASP2	IMP		Human	PMID:17543864
Biological Process	GO:0034453	microtubule anchoring	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:0000226	microtubule cytoskeleton organization	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:0000226	microtubule cytoskeleton organization	CLASP2	IMP		Human	PMID:26003921
Biological Process	GO:0007019	microtubule depolymerization	Clasp2	IMP	MGI:MGI:3693618	Mouse	PMID:17113391
Biological Process	GO:0007020	microtubule nucleation	CLASP2	IMP		Human	PMID:17543864
Biological Process	GO:0031023	microtubule organizing center organization	CLASP2	IMP		Human	PMID:17543864
Biological Process	GO:0007052	mitotic spindle organization	CLASP2	IMP		Human	PMID:16866869
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	Clasp2	IMP	MGI:MGI:3693618	Mouse	PMID:17113391
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	Clasp2	IDA		Mouse	PMID:11290329
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	Clasp2	IDA		Rat	PMID:11290329|RGD:68300
Biological Process	GO:0051497	negative regulation of stress fiber assembly	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:1903690	negative regulation of wound healing, spreading of epidermal cells	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	CLASP2	IMP		Human	PMID:23940118
Biological Process	GO:0010634	positive regulation of epithelial cell migration	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:0045921	positive regulation of exocytosis	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:0090091	positive regulation of extracellular matrix disassembly	CLASP2	IMP		Human	PMID:24859005
Biological Process	GO:1905477	positive regulation of protein localization to membrane	Clasp2	IMP		Rat	PMID:22992739|RGD:28912745
Biological Process	GO:0072659	protein localization to plasma membrane	CLASP2	IMP		Human	PMID:23940118
Biological Process	GO:0010717	regulation of epithelial to mesenchymal transition	CLASP2	IMP		Human	PMID:23940118
Biological Process	GO:0010470	regulation of gastrulation	CLASP2	IMP		Human	PMID:23940118
Biological Process	GO:0031110	regulation of microtubule polymerization or depolymerization	CLASP2	IMP		Human	PMID:11290329
Biological Process	GO:0032886	regulation of microtubule-based process	CLASP2	IMP		Human	PMID:20937854
Biological Process	GO:0006903	vesicle targeting	CLASP2	IMP		Human	PMID:24859005

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern