Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CIAO3
  • Mouse genes Ciao3
  • Rat genes Ciao3
  • Zfish genes narfl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ciao3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CIAO3	IPI	UniProtKB:O76071,UniProtKB:Q9Y3D0	Human	PMID:23585563
Molecular Function	GO:0005515	protein binding	CIAO3	IPI	UniProtKB:Q96T76	Human	PMID:23585563
Molecular Function	GO:0005515	protein binding	CIAO3	IPI	UniProtKB:Q96T76,UniProtKB:Q9Y3D0	Human	PMID:23585563
Cellular Component	GO:0097361	CIA complex	CIAO3	IDA		Human	PMID:22678361
Cellular Component	GO:0097361	CIA complex	CIAO3	IDA		Human	PMID:22678362
Cellular Component	GO:0097361	CIA complex	CIAO3	IDA		Human	PMID:23585563
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Ciao3	IMP		Mouse	PMID:24029230
Biological Process	GO:0032364	intracellular oxygen homeostasis	CIAO3	IDA		Human	PMID:16956324
Biological Process	GO:0016226	iron-sulfur cluster assembly	CIAO3	IMP		Human	PMID:18270200
Biological Process	GO:0016226	iron-sulfur cluster assembly	Ciao3	IMP	MGI:MGI:4946833	Mouse	PMID:21367862
Biological Process	GO:0045765	regulation of angiogenesis	narfl	IMP	ZFIN:ZDB-GENO-170828-1	Zfish	PMID:31677554
Biological Process	GO:0045765	regulation of angiogenesis	narfl	IMP	ZFIN:ZDB-GENO-201008-8	Zfish	PMID:31677554
Biological Process	GO:0010468	regulation of gene expression	CIAO3	IDA		Human	PMID:16956324
Biological Process	GO:0001666	response to hypoxia	CIAO3	IDA		Human	PMID:16956324
Biological Process	GO:0002040	sprouting angiogenesis	narfl	IMP	ZFIN:ZDB-GENO-170828-1	Zfish	PMID:27835862

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern