Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CGN
  • Mouse genes Cgn
  • Rat genes Cgn
  • Zfish genes cgnb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cgn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	CGN	HDA		Human	PMID:25468996
Molecular Function	GO:0008017	microtubule binding	Cgn	IDA		Mouse	PMID:24385485
Molecular Function	GO:0005515	protein binding	CGN	IPI	UniProtKB:Q07157	Human	PMID:11042084
Molecular Function	GO:0005515	protein binding	CGN	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	CGN	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CGN	IPI	UniProtKB:Q9Y4P9	Human	PMID:31473225
Molecular Function	GO:0005515	protein binding	Cgn	IPI	PR:Q5EG47	Mouse	PMID:24385485
Cellular Component	GO:0043296	apical junction complex	Cgn	IDA		Mouse	PMID:15292197
Cellular Component	GO:0005923	bicellular tight junction	CGN	IDA		Human	PMID:22006950
Cellular Component	GO:0005923	bicellular tight junction	Cgn	IDA		Mouse	PMID:22946046
Cellular Component	GO:0005923	bicellular tight junction	Cgn	IDA		Mouse	PMID:24385485
Cellular Component	GO:0005903	brush border	Cgn	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0030054	cell junction	CGN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CGN	IDA		Human	GO_REF:0000052
Biological Process	GO:0070830	bicellular tight junction assembly	Cgn	IMP		Mouse	PMID:24385485
Biological Process	GO:0003382	epithelial cell morphogenesis	Cgn	IMP		Mouse	PMID:24385485
Biological Process	GO:0000226	microtubule cytoskeleton organization	Cgn	IMP		Mouse	PMID:24385485
Biological Process	GO:0048916	posterior lateral line development	cgnb	IMP	ZFIN:ZDB-MRPHLNO-221209-3	Zfish	PMID:35600071

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern