Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CFC1,CFC1B
  • Mouse genes Cfc1
  • Rat genes Cfc1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cfc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070697	activin receptor binding	Cfc1	IPI	UniProtKB:P36896	Mouse	MGI:MGI:5318034|PMID:12052855
Molecular Function	GO:0038100	nodal binding	CFC1	IPI	UniProtKB:P43021	Human	PMID:12052855
Biological Process	GO:0048856	anatomical structure development	Cfc1	IGI	MGI:MGI:97451	Mouse	PMID:11412024
Biological Process	GO:0009952	anterior/posterior pattern specification	Cfc1	IGI	MGI:MGI:97451	Mouse	PMID:11412024
Biological Process	GO:0060413	atrial septum morphogenesis	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0060976	coronary vasculature development	Cfc1	IMP		Mouse	PMID:25807483
Biological Process	GO:0007368	determination of left/right symmetry	Cfc1	IMP		Mouse	PMID:25807483
Biological Process	GO:0007368	determination of left/right symmetry	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0048546	digestive tract morphogenesis	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0007492	endoderm development	Cfc1	IGI	MGI:MGI:97451	Mouse	PMID:11412024
Biological Process	GO:0007565	female pregnancy	Cfc1	IEP		Rat	PMID:31418961|RGD:155230829
Biological Process	GO:0001947	heart looping	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0003007	heart morphogenesis	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0060460	left lung morphogenesis	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0001889	liver development	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0038092	nodal signaling pathway	CFC1	IMP		Human	PMID:12052855
Biological Process	GO:0038092	nodal signaling pathway	Cfc1	IMP		Mouse	MGI:MGI:5318034|PMID:12052855
Biological Process	GO:0009791	post-embryonic development	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0060541	respiratory system development	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397
Biological Process	GO:0048536	spleen development	Cfc1	IMP	MGI:MGI:2179530	Mouse	PMID:10521397

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern