Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CFB
  • Mouse genes Cfb
  • Rat genes
  • Zfish genes bfb,cfb,cfbl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cfb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CFB	IPI	UniProtKB:P01024	Human	PMID:19255449
Molecular Function	GO:0005515	protein binding	CFB	IPI	UniProtKB:Q92496-1	Human	PMID:22518841
Molecular Function	GO:0005515	protein binding	CFB	IPI	UniProtKB:Q92496-3	Human	PMID:22518841
Molecular Function	GO:0005515	protein binding	CFB	IPI	UniProtKB:Q92496-3	Human	PMID:28533443
Cellular Component	GO:0072562	blood microparticle	CFB	HDA		Human	PMID:22516433
Cellular Component	GO:0070062	extracellular exosome	CFB	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	CFB	HDA		Human	PMID:16502470
Biological Process	GO:0006957	complement activation, alternative pathway	Cfb	IGI		Mouse	PMID:27564415
Biological Process	GO:0006957	complement activation, alternative pathway	Cfb	IMP		Mouse	PMID:27564415
Biological Process	GO:0006957	complement activation, alternative pathway	Cfb	IMP	MGI:MGI:1861129	Mouse	PMID:9238044
Biological Process	GO:0042742	defense response to bacterium	cfb	IDA		Zfish	PMID:29572872
Biological Process	GO:0006955	immune response	cfb	IDA		Zfish	PMID:29572872
Biological Process	GO:0009617	response to bacterium	cfbl	IDA		Zfish	PMID:15829308
Biological Process	GO:0009617	response to bacterium	cfb	IDA		Zfish	PMID:17055441

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern