Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cdk9

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CDK9
- Mouse genes Cdk9
- Rat genes Cdk9
- Zfish genes cdk9
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097322	7SK snRNA binding	CDK9	IDA		Human	PMID:11713533
Molecular Function	GO:0003682	chromatin binding	Cdk9	IDA		Mouse	MGI:MGI:5763368\|PMID:16245309
Molecular Function	GO:0003682	chromatin binding	Cdk9	IDA		Mouse	PMID:23154982
Molecular Function	GO:0003682	chromatin binding	Cdk9	IDA		Rat	PMID:20081228\|RGD:9698419
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	CDK9	IDA		Human	PMID:12037670
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	CDK9	IDA		Human	PMID:14701750
Molecular Function	GO:0003677	DNA binding	CDK9	IDA		Human	PMID:16109376
Molecular Function	GO:0140677	molecular function activator activity	CDK9	IDA		Human	PMID:29335245
Molecular Function	GO:0140678	molecular function inhibitor activity	CDK9	IDA		Human	PMID:14701750
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:12832472
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:14580347
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q9UHK0	Human	PMID:15107825
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P40763	Human	PMID:15286705
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563\|UniProtKB:O60583	Human	PMID:15563843
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q96MH2	Human	PMID:15713662
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583-2	Human	PMID:16331689
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60885-1	Human	PMID:17690245
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q4G0J3	Human	PMID:18281698
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:18483487
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:18483487
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q4G0J3	Human	PMID:18483487
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:18566585
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:19387490
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:19914168
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:20153263
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:20535204
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P04608	Human	PMID:20535204
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:20562857
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:20562857
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P04608	Human	PMID:20562857
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q4G0J3	Human	PMID:20562857
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q13535	Human	PMID:20930849
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q8WXE1	Human	PMID:20930849
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q9HAW4	Human	PMID:20930849
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:21533037
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:21533037
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P04608	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:22959624
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P07900	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P08238	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q13451	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q16543	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q4G0J3	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q13451	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q4G0J3	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q16543	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563,UniProtKB:O60885,UniProtKB:Q6NYC1	Human	PMID:24360279
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:24360279
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q6NYC1	Human	PMID:24360279
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q13451	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q16543	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P07900	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q13451	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:25470060
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:26659056
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60885-1	Human	PMID:26659056
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q4G0J3	Human	PMID:26659056
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P53041	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q9NRC8	Human	PMID:28426094
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992,UniProtKB:P24928	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992,UniProtKB:Q4G0J3,UniProtKB:Q7L2J0	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992,UniProtKB:Q4G0J3,UniProtKB:Q9Y580	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P24928,UniProtKB:Q9Y580	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P42285,UniProtKB:Q4G0J3	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q4G0J3,UniProtKB:Q9Y580	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O94992	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P07900	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q13451	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q16543	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:Q4G0J3	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60563	Human	PMID:9499409
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583	Human	PMID:9499409
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583-1	Human	PMID:9499409
Molecular Function	GO:0005515	protein binding	CDK9	IPI	UniProtKB:O60583-2	Human	PMID:9499409
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	UniProtKB:Q62093	Mouse	MGI:MGI:5553217\|PMID:23663783
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	UniProtKB:Q62093	Mouse	MGI:MGI:5918739\|PMID:18641664
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	UniProtKB:P10085	Mouse	MGI:MGI:5706918\|PMID:12037670
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	UniProtKB:Q91Y44	Mouse	MGI:MGI:5514133\|PMID:20593818
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	UniProtKB:Q6ZQL4	Mouse	MGI:MGI:6323527\|PMID:31128943
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	UniProtKB:Q91Y44	Mouse	MGI:MGI:5447877\|PMID:22922464
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	UniProtKB:P28574	Mouse	MGI:MGI:4839428\|PMID:20434984
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	PR:Q9ESU6	Mouse	PMID:23154982
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	PR:P15314	Mouse	PMID:23154982
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	PR:Q03267	Mouse	PMID:21245044
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	PR:O54943	Mouse	PMID:22767893
Molecular Function	GO:0005515	protein binding	Cdk9	IPI	PR:P17679	Mouse	PMID:21245044
Molecular Function	GO:0019901	protein kinase binding	Cdk9	IDA		Mouse	PMID:22547058
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK9	IDA		Human	PMID:14701750
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK9	IDA		Human	PMID:28431135
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK9	IDA		Human	PMID:29335245
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Cdk9	IDA		Mouse	PMID:21245044
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	CDK9	IDA		Human	PMID:12721286
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	CDK9	IDA		Human	PMID:28426094
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	CDK9	IDA		Human	PMID:29849146
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	CDK9	IDA		Human	PMID:9499409
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	Cdk9	IMP		Mouse	PMID:22509028
Molecular Function	GO:0017069	snRNA binding	Cdk9	IDA		Mouse	PMID:16109376
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Cdk9	IDA		Mouse	MGI:MGI:4834059\|PMID:20570862
Molecular Function	GO:0001223	transcription coactivator binding	CDK9	IPI	UniProtKB:P06400	Human	PMID:12037672
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	CDK9	IPI		Human	PMID:18566585
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	CDK9	IPI		Human	PMID:9499409
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	CDK9	IDA		Human	PMID:15905409
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	CDK9	IDA		Human	PMID:9499409
Cellular Component	GO:0008024	cyclin/CDK positive transcription elongation factor complex	Cdk9	IDA		Mouse	PMID:23752591
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	CDK9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	CDK9	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	CDK9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CDK9	IDA		Human	PMID:14701750
Cellular Component	GO:0005634	nucleus	CDK9	IDA		Human	PMID:29849146
Cellular Component	GO:0005634	nucleus	CDK9	IDA		Human	PMID:16109376
Cellular Component	GO:0005634	nucleus	CDK9	IDA		Human	PMID:9499409
Cellular Component	GO:0005634	nucleus	Cdk9	IDA		Mouse	PMID:22767893
Cellular Component	GO:0005634	nucleus	Cdk9	IDA		Mouse	PMID:16109376
Cellular Component	GO:0005634	nucleus	Cdk9	IDA		Rat	PMID:20081228\|RGD:9698419
Cellular Component	GO:0070691	P-TEFb complex	CDK9	IDA		Human	PMID:18483487
Cellular Component	GO:0070691	P-TEFb complex	CDK9	IDA		Human	PMID:30134174
Cellular Component	GO:0016605	PML body	CDK9	IDA		Human	PMID:18250157
Cellular Component	GO:0008023	transcription elongation factor complex	CDK9	IDA		Human	PMID:22195968
Biological Process	GO:0061026	cardiac muscle tissue regeneration	cdk9	IGI	ZFIN:ZDB-GENE-030131-6896	Zfish	PMID:26542022
Biological Process	GO:0061026	cardiac muscle tissue regeneration	cdk9	IMP	ZFIN:ZDB-MRPHLNO-100728-5	Zfish	PMID:26542022
Biological Process	GO:0071345	cellular response to cytokine stimulus	CDK9	IDA		Human	PMID:17956865
Biological Process	GO:0090594	inflammatory response to wounding	cdk9	IMP	ZFIN:ZDB-GENO-180530-5	Zfish	PMID:27833165
Biological Process	GO:0120186	negative regulation of protein localization to chromatin	CDK9	IDA		Human	PMID:14701750
Biological Process	GO:0043923	positive regulation by host of viral transcription	CDK9	IDA		Human	PMID:10866664
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	Cdk9	IMP		Rat	PMID:20081228\|RGD:9698419
Biological Process	GO:0120187	positive regulation of protein localization to chromatin	CDK9	IDA		Human	PMID:29335245
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CDK9	IDA		Human	PMID:29335245
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	CDK9	IDA		Human	PMID:14701750
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	CDK9	IDA		Human	PMID:29849146
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	CDK9	IDA		Human	PMID:30134174
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	CDK9	IDA		Human	PMID:9499409
Biological Process	GO:0006468	protein phosphorylation	CDK9	IDA		Human	PMID:16109376
Biological Process	GO:0006468	protein phosphorylation	CDK9	IDA		Human	PMID:9499409
Biological Process	GO:0065003	protein-containing complex assembly	cdk9	IPI	ZFIN:ZDB-GENE-030131-321,ZFIN:ZDB-GENE-030131-4637,ZFIN:ZDB-GENE-030131-6397	Zfish	PMID:31183407
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	cdk9	IMP	ZFIN:ZDB-MRPHLNO-100728-5	Zfish	PMID:26542022
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	cdk9	IGI	ZFIN:ZDB-GENE-030131-6896	Zfish	PMID:26542022
Biological Process	GO:0051726	regulation of cell cycle	CDK9	IDA		Human	PMID:20930849
Biological Process	GO:0006282	regulation of DNA repair	CDK9	IDA		Human	PMID:20493174
Biological Process	GO:0031056	regulation of histone modification	CDK9	IDA		Human	PMID:19844166
Biological Process	GO:0031440	regulation of mRNA 3'-end processing	CDK9	IMP		Human	PMID:19575011
Biological Process	GO:0031440	regulation of mRNA 3'-end processing	Cdk9	IMP		Mouse	MGI:MGI:5616315\|PMID:19575011
Biological Process	GO:0051147	regulation of muscle cell differentiation	CDK9	IMP		Human	PMID:12037670
Biological Process	GO:0031297	replication fork processing	CDK9	IDA		Human	PMID:20930849
Biological Process	GO:0009410	response to xenobiotic stimulus	Cdk9	IEP		Rat	PMID:20828602\|RGD:9698426
Biological Process	GO:0006366	transcription by RNA polymerase II	CDK9	IDA		Human	PMID:28426094

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.