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Cdk9
Gene Detail
 Symbol
Name
ID
Cdk9
cyclin-dependent kinase 9 (CDC2-related kinase)
MGI:1328368
Synonyms PITALRE
Feature Type protein coding gene
Genetic Map
Chromosome 2
22.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:32705784-32713076 bp, - strand
From VEGA annotation of GRCm38

  7293 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55566  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Cdk9

Human
homologs
Human Homolog CDK9, cyclin-dependent kinase 9
NCBI Gene ID 1025
neXtProt AC  NX_P50750
Human Synonyms  C-2k, CDC2L4, CTK1, PITALRE, TAK
Human Chr (Location)  9q34.1; chr9:127786026-127790773 (+)  GRCh38
Alleles
and
phenotypes
All alleles(8) : Targeted(3) Gene trapped(5)
Gene Ontology
(GO)
classifications
All GO classifications: (39 annotations)
Process cellular response to cytokine stimulus, cellular response to DNA damage stimulus, ...
Component cytoplasm, intracellular membrane-bounded organelle, ...
Function ATP binding, chromatin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (24)    Tissues (23)   
Theiler Stages: 15, 17, 19, 28
Assay TypeResults
RNA in situ 14
Western blot 10
cDNA source data(131)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(132) cDNA(131) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000012534 (Evidence)
Ensembl Gene ModelENSMUSG00000009555 (Evidence)
Entrez Gene107951 (Evidence)
UniGene27557
DFCITC1575385, TC1709346
DoTSDT.101735411, DT.533908, DT.55238959
NIA Mouse Gene IndexU022507, U370087, U377781
EC2.7.11.22, 2.7.11.23
Consensus CDS ProjectCCDS15927.1
International Mouse Knockout Project StatusCdk9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012534 VEGA Gene Model | MGI Sequence Detail 7293 C57BL/6J ±  kb
transcript OTTMUST00000029807 VEGA | MGI Sequence Detail 1733 Not Applicable 
polypeptide OTTMUSP00000013406 VEGA | MGI Sequence Detail 372 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(2) UniProt(4)
Polymorphisms RFLP(1) : SNPs within 2kb(2 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000005267 cyclin-dependent kinase 9
References (Earliest) J:50128 Bagella L, et al., Cloning of murine CDK9/PITALRE and its tissue-specific expression in development. J Cell Physiol. 1998 Nov;177(2):206-13
(Latest) J:206891 Ji X, et al., SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase. Cell. 2013 May 9;153(4):855-68
All references(53)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory