Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC42BPA
  • Mouse genes Cdc42bpa
  • Rat genes Cdc42bpa
  • Zfish genes cdc42bpaa,cdc42bpab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc42bpa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	CDC42BPA	IDA		Human	PMID:9092543
Molecular Function	GO:0005524	ATP binding	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451
Molecular Function	GO:0042802	identical protein binding	CDC42BPA	IPI	UniProtKB:Q5VT25	Human	PMID:11283256
Molecular Function	GO:0042802	identical protein binding	CDC42BPA	IPI	UniProtKB:Q5VT25	Human	PMID:23414517
Molecular Function	GO:0042802	identical protein binding	Cdc42bpa	IPI	UniProtKB:O54874	Rat	PMID:11283256|RGD:8554633
Molecular Function	GO:0042802	identical protein binding	Cdc42bpa	IPI	UniProtKB:O54874	Rat	PMID:9418861|RGD:632451
Molecular Function	GO:0000287	magnesium ion binding	CDC42BPA	IDA		Human	PMID:9092543
Molecular Function	GO:0000287	magnesium ion binding	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451
Molecular Function	GO:0005515	protein binding	CDC42BPA	IPI	UniProtKB:O92972:PRO_0000278742	Human	PMID:10644344
Molecular Function	GO:0005515	protein binding	CDC42BPA	IPI	UniProtKB:P60953	Human	PMID:15194684
Molecular Function	GO:0005515	protein binding	CDC42BPA	IPI	UniProtKB:P60953	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	CDC42BPA	IPI	UniProtKB:P60953	Human	PMID:9418861
Molecular Function	GO:0005515	protein binding	Cdc42bpa	IPI	UniProtKB:Q9QUI1	Mouse	MGI:MGI:5908532|PMID:25107909
Molecular Function	GO:0005515	protein binding	Cdc42bpa	IPI	UniProtKB:D4A8G3	Rat	PMID:18854160|RGD:8553532
Molecular Function	GO:0005515	protein binding	Cdc42bpa	IPI	UniProtKB:Q566R4	Rat	PMID:25107909|RGD:13210541
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDC42BPA	IDA		Human	PMID:11340065
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDC42BPA	IDA		Human	PMID:11399775
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDC42BPA	IDA		Human	PMID:21457715
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDC42BPA	IDA		Human	PMID:9092543
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451
Cellular Component	GO:0042641	actomyosin	CDC42BPA	IDA		Human	PMID:18854160
Cellular Component	GO:0042641	actomyosin	Cdc42bpa	IDA		Rat	PMID:18854160|RGD:8553532
Cellular Component	GO:0031252	cell leading edge	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451
Cellular Component	GO:0005911	cell-cell junction	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451
Cellular Component	GO:0070062	extracellular exosome	CDC42BPA	HDA		Human	PMID:19056867
Cellular Component	GO:0030027	lamellipodium	Cdc42bpa	IDA		Mouse	MGI:MGI:5908532|PMID:25107909
Biological Process	GO:0031532	actin cytoskeleton reorganization	CDC42BPA	IDA		Human	PMID:9418861
Biological Process	GO:0031532	actin cytoskeleton reorganization	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451
Biological Process	GO:0031032	actomyosin structure organization	CDC42BPA	IMP		Human	PMID:18854160
Biological Process	GO:0031032	actomyosin structure organization	Cdc42bpa	IMP		Rat	PMID:18854160|RGD:8553532
Biological Process	GO:0016477	cell migration	CDC42BPA	IMP		Human	PMID:18854160
Biological Process	GO:0016477	cell migration	Cdc42bpa	IMP		Rat	PMID:18854160|RGD:8553532
Biological Process	GO:0007010	cytoskeleton organization	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451
Biological Process	GO:0000226	microtubule cytoskeleton organization	Cdc42bpa	IMP		Mouse	PMID:15882626
Biological Process	GO:0007097	nuclear migration	Cdc42bpa	IMP		Mouse	PMID:15882626
Biological Process	GO:0006468	protein phosphorylation	CDC42BPA	IDA		Human	PMID:9092543
Biological Process	GO:0006468	protein phosphorylation	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451
Biological Process	GO:0051056	regulation of small GTPase mediated signal transduction	Cdc42bpa	IDA		Rat	PMID:9418861|RGD:632451

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern