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Cdc42bpa Gene Detail
Summary
  • Symbol
    Cdc42bpa
  • Name
    CDC42 binding protein kinase alpha
  • Synonyms
    A930014J19Rik, DMPK-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441841
    NCBI Gene: 226751
  • Gene Overview
    MyGene.info: CDC42BPA
Location & Maps
more
  • Sequence Map
    Chr1:179960472-180165603 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      205132 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 84.01 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CDC42BPA, CDC42 binding protein kinase alpha
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CDC42BPA, CDC42 binding protein kinase alpha
    Orthology source: HomoloGene
  • Synonyms
    MRCK, MRCKA, PK428
  • Links
    NCBI Gene ID: 8476
    neXtProt AC: NX_Q5VT25

  • Chr Location
    1q42.11; chr1:226989858-227318492 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Cdc42bpa
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021765 VEGA Gene Model | MGI Sequence Detail 205132 C57BL/6J ±  kb
transcript OTTMUST00000051658 VEGA | MGI Sequence Detail 9161 Not Applicable  
polypeptide OTTMUSP00000024352 VEGA | MGI Sequence Detail 1732 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1359 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 5
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:214095 Osipovich AB, et al., Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Development. 2014 Aug;141(15):2939-49

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory