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Cdc42bpa Gene Detail
Summary
  • Symbol
    Cdc42bpa
  • Name
    CDC42 binding protein kinase alpha
  • Synonyms
    A930014J19Rik, DMPK-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441841
    NCBI Gene: 226751
  • Gene Overview
    MyGene.info: CDC42BPA
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:179960472-180165603 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 84.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1359 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441841
protein coding gene Chr1:179959968-180165606 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016865
protein coding gene Chr1:186364044-186580261 (+)
A/J MGP_AJ_G0016844
protein coding gene Chr1:178839538-179042068 (+)
AKR/J MGP_AKRJ_G0016810
protein coding gene Chr1:184149127-184364581 (+)
BALB/cJ MGP_BALBcJ_G0016802
protein coding gene Chr1:179459942-179664707 (+)
C3H/HeJ MGP_C3HHeJ_G0016627
protein coding gene Chr1:184916685-185126259 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017265
protein coding gene Chr1:192386542-192603400 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014973
protein coding gene Chr1:169817495-170019201 (+)
CAST/EiJ MGP_CASTEiJ_G0016208
protein coding gene Chr1:184217519-184442696 (+)
CBA/J MGP_CBAJ_G0016601
protein coding gene Chr1:199541938-199752498 (+)
DBA/2J MGP_DBA2J_G0016707
protein coding gene Chr1:177676627-177878784 (+)
FVB/NJ MGP_FVBNJ_G0016703
protein coding gene Chr1:175769073-175971358 (+)
LP/J MGP_LPJ_G0016781
protein coding gene Chr1:187629406-187843152 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016734
protein coding gene Chr1:206697779-206961150 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017302
protein coding gene Chr1:183907727-184137503 (+)
PWK/PhJ MGP_PWKPhJ_G0015996
protein coding gene Chr1:176756293-176962272 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015772
protein coding gene Chr1:182842526-183063694 (+)
WSB/EiJ MGP_WSBEiJ_G0016271
protein coding gene Chr1:184116278-184335928 (+)



Homology
more
  • Human Ortholog
    CDC42BPA, CDC42 binding protein kinase alpha
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CDC42BPA, CDC42 binding protein kinase alpha
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MRCK, MRCKA, PK428
  • Links
    NCBI Gene ID: 8476
    neXtProt AC: NX_Q5VT25
    UniProt: Q5VT25

  • Chr Location
    1q42.13; chr1:226989865-227318492 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026490 Ensembl Gene Model | MGI Sequence Detail 205132 C57BL/6J ±  kb
transcript ENSMUST00000212756 Ensembl | MGI Sequence Detail 5247 Not Applicable  
polypeptide ENSMUSP00000148469 Ensembl | MGI Sequence Detail 1748 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 5
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:238168 Dobrowolski SF, et al., DNA methylation in the pathophysiology of hyperphenylalaninemia in the PAH(enu2) mouse model of phenylketonuria. Mol Genet Metab. 2016 Sep;119(1-2):1-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory