Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD6
  • Mouse genes Cd6
  • Rat genes Cd6
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	CD6	IPI	UniProtKB:P30203	Human	PMID:26146185
Molecular Function	GO:0001530	lipopolysaccharide binding	CD6	IDA		Human	PMID:17601777
Molecular Function	GO:0070891	lipoteichoic acid binding	CD6	IMP		Human	PMID:17601777
Molecular Function	GO:0005515	protein binding	CD6	IPI	UniProtKB:Q13094	Human	PMID:24584089
Molecular Function	GO:0005515	protein binding	CD6	IPI	UniProtKB:P09382	Human	PMID:24945728
Molecular Function	GO:0005515	protein binding	CD6	IPI	UniProtKB:P17931	Human	PMID:24945728
Molecular Function	GO:0005515	protein binding	CD6	IPI	UniProtKB:Q13740	Human	PMID:24945728
Molecular Function	GO:0005515	protein binding	CD6	IPI	UniProtKB:Q13740	Human	PMID:26146185
Molecular Function	GO:0005515	protein binding	Cd6	IPI	UniProtKB:Q60787	Mouse	MGI:MGI:5568870|PMID:24584089
Molecular Function	GO:0005515	protein binding	Cd6	IPI	PR:Q61490	Mouse	PMID:9209500
Molecular Function	GO:0005515	protein binding	Cd6	IPI	RGD:2309	Rat	PMID:12525577|RGD:1298743
Molecular Function	GO:0019901	protein kinase binding	Cd6	IDA		Rat	PMID:12525577|RGD:1298743
Cellular Component	GO:0009986	cell surface	Cd6	IDA		Rat	PMID:12525577|RGD:1298743
Cellular Component	GO:0001772	immunological synapse	CD6	IDA		Human	PMID:15294938
Cellular Component	GO:0005886	plasma membrane	CD6	IDA		Human	PMID:15294938
Biological Process	GO:0002438	acute inflammatory response to antigenic stimulus	CD6	IDA		Human	PMID:17601777
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	CD6	IMP		Human	PMID:16352806
Biological Process	GO:0001771	immunological synapse formation	CD6	IMP		Human	PMID:15294938
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	CD6	IDA		Human	PMID:17601777
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	CD6	IDA		Human	PMID:17601777
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Cd6	IDA		Rat	PMID:12525577|RGD:1298743
Biological Process	GO:0042102	positive regulation of T cell proliferation	CD6	IMP		Human	PMID:15294938
Biological Process	GO:0032496	response to lipopolysaccharide	CD6	IDA		Human	PMID:17601777

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern