Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD47
  • Mouse genes Cd47
  • Rat genes Cd47
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd47

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0098632	cell-cell adhesion mediator activity	CD47	IPI	UniProtKB:P78324	Human	PMID:11509594
Molecular Function	GO:0005515	protein binding	CD47	IPI	UniProtKB:Q9P1W8	Human	PMID:15383453
Molecular Function	GO:0005515	protein binding	CD47	IPI	UniProtKB:P78324	Human	PMID:24026300
Molecular Function	GO:0005515	protein binding	CD47	IPI	UniProtKB:Q8N205	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Cd47	IPI	PR:P97797	Mouse	PMID:14634079
Molecular Function	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	Cd47	IPI	UniProtKB:P97710	Rat	PMID:16055727|RGD:13792550
Molecular Function	GO:0070053	thrombospondin receptor activity	CD47	IPI	UniProtKB:P07996	Human	PMID:15700281
Cellular Component	GO:0009986	cell surface	CD47	IDA		Human	PMID:11509594
Cellular Component	GO:0009986	cell surface	Cd47	IDA		Rat	PMID:12023387|RGD:625650
Cellular Component	GO:0009986	cell surface	Cd47	IDA		Rat	PMID:21401967|RGD:13792533
Cellular Component	GO:0070062	extracellular exosome	Cd47	IDA		Mouse	PMID:19724054
Cellular Component	GO:0005886	plasma membrane	Cd47	IDA		Mouse	PMID:14634079
Biological Process	GO:1904669	ATP export	CD47	IDA		Human	PMID:24022490
Biological Process	GO:0016477	cell migration	Cd47	IDA		Rat	PMID:12023387|RGD:625650
Biological Process	GO:0071347	cellular response to interleukin-1	Cd47	IMP		Rat	PMID:12023387|RGD:625650
Biological Process	GO:0071349	cellular response to interleukin-12	CD47	IMP		Human	PMID:11509594
Biological Process	GO:0071346	cellular response to type II interferon	Cd47	IMP		Rat	PMID:12023387|RGD:625650
Biological Process	GO:0006954	inflammatory response	Cd47	IDA		Mouse	PMID:28228282
Biological Process	GO:0070487	monocyte aggregation	Cd47	IMP		Mouse	PMID:28228282
Biological Process	GO:1905450	negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	Cd47	IMP		Rat	PMID:21401967|RGD:13792533
Biological Process	GO:0008228	opsonization	Cd47	IDA		Mouse	PMID:14634079
Biological Process	GO:0008284	positive regulation of cell population proliferation	CD47	IDA		Human	PMID:15383453
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	CD47	IDA		Human	PMID:15383453
Biological Process	GO:0050729	positive regulation of inflammatory response	Cd47	IMP	MGI:MGI:1861955	Mouse	PMID:10816079
Biological Process	GO:2000439	positive regulation of monocyte extravasation	Cd47	IMP		Rat	PMID:12023387|RGD:625650
Biological Process	GO:0050766	positive regulation of phagocytosis	Cd47	IDA		Mouse	PMID:14634079
Biological Process	GO:0050766	positive regulation of phagocytosis	Cd47	IMP		Rat	PMID:23238794|RGD:8696010
Biological Process	GO:0051496	positive regulation of stress fiber assembly	Cd47	IMP		Rat	PMID:12023387|RGD:625650
Biological Process	GO:0050870	positive regulation of T cell activation	CD47	IDA		Human	PMID:15383453
Biological Process	GO:0032653	regulation of interleukin-10 production	CD47	IMP		Human	PMID:11509594
Biological Process	GO:0032655	regulation of interleukin-12 production	CD47	IMP		Human	PMID:11509594
Biological Process	GO:0032675	regulation of interleukin-6 production	CD47	IMP		Human	PMID:11509594
Biological Process	GO:0045428	regulation of nitric oxide biosynthetic process	Cd47	IDA		Mouse	MGI:MGI:6201986|PMID:16055727
Biological Process	GO:0032680	regulation of tumor necrosis factor production	CD47	IMP		Human	PMID:11509594
Biological Process	GO:0032649	regulation of type II interferon production	CD47	IMP		Human	PMID:11509594
Biological Process	GO:0009617	response to bacterium	Cd47	IMP	MGI:MGI:1861955	Mouse	PMID:10816079

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern