Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCR3
  • Mouse genes Ccr3
  • Rat genes Ccr3
  • Zfish genes cabz01093075.1,ccr11.1,ccr2,ccr8.1,si:cabz01093077.1,si:ch211-207g17.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccr3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019957	C-C chemokine binding	CCR3	IDA		Human	PMID:11425309
Molecular Function	GO:0019957	C-C chemokine binding	Ccr3	IPI	UniProtKB:Q9Y4X3	Mouse	MGI:MGI:5897759|PMID:12538707
Molecular Function	GO:0016493	C-C chemokine receptor activity	Ccr3	IDA		Mouse	PMID:7594543
Molecular Function	GO:0005515	protein binding	CCR3	IPI	UniProtKB:P51671	Human	PMID:23597562
Molecular Function	GO:0005515	protein binding	Ccr3	IPI	PR:P10855	Mouse	PMID:7594543
Cellular Component	GO:0005768	endosome	Ccr3	IDA		Rat	PMID:12004163|RGD:632389
Cellular Component	GO:0005615	extracellular space	Ccr3	IDA		Rat	PMID:12004163|RGD:632389
Cellular Component	GO:0005886	plasma membrane	CCR3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Ccr3	IDA		Rat	PMID:12004163|RGD:632389
Biological Process	GO:0035476	angioblast cell migration	Ccr3	IMP		Rat	PMID:18954648|RGD:4890013
Biological Process	GO:0006935	chemotaxis	Ccr3	IDA		Mouse	PMID:7594543
Biological Process	GO:0048245	eosinophil chemotaxis	Ccr3	IMP		Rat	PMID:16978084|RGD:4145646
Biological Process	GO:0070371	ERK1 and ERK2 cascade	Ccr3	IGI	RGD:619755	Rat	PMID:12413953|RGD:4145648
Biological Process	GO:0002551	mast cell chemotaxis	Ccr3	IMP		Rat	PMID:12413953|RGD:4145648
Biological Process	GO:0042117	monocyte activation	ccr2	IMP	ZFIN:ZDB-MRPHLNO-171025-3	Zfish	PMID:28844797
Biological Process	GO:0045766	positive regulation of angiogenesis	CCR3	IMP		Human	PMID:19525930
Biological Process	GO:0045766	positive regulation of angiogenesis	Ccr3	IMP		Mouse	MGI:MGI:3850576|PMID:19525930
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	Ccr3	IMP		Mouse	MGI:MGI:3850576|PMID:19525930

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern