Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CASZ1
  • Mouse genes Casz1
  • Rat genes Casz1
  • Zfish genes casz1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Casz1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CASZ1	IDA		Human	PMID:27693370
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	CASZ1	IDA		Human	PMID:27693370
Cellular Component	GO:0000785	chromatin	CASZ1	IDA		Human	PMID:27693370
Cellular Component	GO:0005829	cytosol	CASZ1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CASZ1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CASZ1	IDA		Human	GO_REF:0000052
Biological Process	GO:0030154	cell differentiation	Casz1	IMP	MGI:MGI:3052661,MGI:MGI:4841554	Mouse	PMID:25654255
Biological Process	GO:1902870	negative regulation of amacrine cell differentiation	Casz1	IMP	MGI:MGI:3052661,MGI:MGI:4841554	Mouse	PMID:25654255
Biological Process	GO:0045686	negative regulation of glial cell differentiation	Casz1	IMP	MGI:MGI:3052661,MGI:MGI:4841554	Mouse	PMID:25654255
Biological Process	GO:0045665	negative regulation of neuron differentiation	Casz1	IMP	MGI:MGI:3052661,MGI:MGI:4841554	Mouse	PMID:25654255
Biological Process	GO:0060226	negative regulation of retinal cone cell fate commitment	Casz1	IMP	MGI:MGI:3052661,MGI:MGI:4841554	Mouse	PMID:25654255
Biological Process	GO:0030182	neuron differentiation	Casz1	IMP	MGI:MGI:3052661,MGI:MGI:4841554	Mouse	PMID:25654255
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	CASZ1	IDA		Human	PMID:27693370
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CASZ1	IDA		Human	PMID:27693370
Biological Process	GO:0060019	radial glial cell differentiation	Casz1	IMP	MGI:MGI:3052661,MGI:MGI:4841554	Mouse	PMID:25654255
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Casz1	IDA		Mouse	PMID:24467707
Biological Process	GO:0060223	retinal rod cell fate commitment	Casz1	IMP	MGI:MGI:3052661,MGI:MGI:4841554	Mouse	PMID:25654255
Biological Process	GO:0060223	retinal rod cell fate commitment	Casz1	IDA		Mouse	PMID:25654255

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern