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Casz1
Gene Detail
Symbol

Name
ID
Casz1
castor zinc finger 1
MGI:1196251
Synonyms
2410019P08Rik, castor, Cst, D4Ertd432e, MGC:31683
Feature Type
protein coding gene
Genetic Map
Chromosome 4
78.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr4:148804429-148954889 bp, + strand
From VEGA annotation of GRCm38

  150461 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9824  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CASZ1
Gene Tree: Casz1

Human
homologs
CASZ1, castor zinc finger 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 54897
neXtProt AC: NX_Q86V15

Human Synonyms: CAS11, CST, dJ734G22.1, SRG, ZNF693

Human Chr (Location): 1p36.22; chr1:10636604-10796676 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(325) : Gene trapped(319) Targeted(6)
Genomic Mutations involving Casz1 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Casz1 interacts with 372 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (147)    Tissues (81)    Images (46)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 147
cDNA source data(41)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase casz1 ; ZFIN casz1    NEW 
Molecular
reagents
All nucleic(44) cDNA(43) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000010931 (Evidence)
Ensembl Gene Model ENSMUSG00000028977 (Evidence)
Entrez Gene 69743 (Evidence)
UniGene 233879
DFCI TC1587350, TC1596664, TC1597328, TC1615524, TC1653796, TC1660030
DoTS DT.101128465, DT.522951, DT.523861, DT.94168276, DT.94222128, DT.97356532, DT.97401015, DT.97401244
NIA Mouse Gene Index U061837, U237652
Consensus CDS Project CCDS38973.1, CCDS51379.1
International Mouse Phenotyping Consortium Status Casz1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010931 VEGA Gene Model | MGI Sequence Detail 150461 C57BL/6J ±  kb
transcript OTTMUST00000025638 VEGA | MGI Sequence Detail 7926 Not Applicable 
polypeptide OTTMUSP00000011748 VEGA | MGI Sequence Detail 1762 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(18) UniProt(7)
Polymorphisms
SNPs within 2kb(1103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
Protein Ontology PR:000006163 zinc finger protein castor homolog 1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:221324 Dorr KM, et al., Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development. Development. 2015 Jun 1;142(11):2037-47
All references(47)
Other
accession IDs
MGI:1916993, MGI:2140527, MGI:2673697, MGI:3039630

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory