Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CARTPT
  • Mouse genes Cartpt
  • Rat genes Cartpt
  • Zfish genes cart2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cartpt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CARTPT	IPI	UniProtKB:P13688	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	CARTPT	IPI	UniProtKB:P40199	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	CARTPT	IPI	UniProtKB:O14770-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cartpt	IPI	RGD:62054	Rat	PMID:17064765|RGD:1625193
Cellular Component	GO:0005615	extracellular space	CARTPT	IDA		Human	PMID:11711504
Cellular Component	GO:0005615	extracellular space	Cartpt	IDA		Mouse	MGI:MGI:1203479|PMID:9590691
Cellular Component	GO:0005615	extracellular space	Cartpt	IDA		Rat	PMID:9590691|RGD:8554847
Cellular Component	GO:0030141	secretory granule	CARTPT	IDA		Human	PMID:21624661
Biological Process	GO:0008343	adult feeding behavior	Cartpt	IDA		Mouse	MGI:MGI:1203479|PMID:9590691
Biological Process	GO:0008343	adult feeding behavior	Cartpt	IDA		Rat	PMID:9590691|RGD:8554847
Biological Process	GO:0009267	cellular response to starvation	Cartpt	IDA		Mouse	MGI:MGI:1203479|PMID:9590691
Biological Process	GO:0009267	cellular response to starvation	Cartpt	IDA		Rat	PMID:15680948|RGD:8553315
Biological Process	GO:0009267	cellular response to starvation	Cartpt	IDA		Rat	PMID:9590691|RGD:8554847
Biological Process	GO:0032922	circadian regulation of gene expression	Cartpt	IDA		Rat	PMID:15680948|RGD:8553315
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Cartpt	IDA		Mouse	MGI:MGI:3696614|PMID:15908120
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Cartpt	IDA		Rat	PMID:15908120|RGD:8554672
Biological Process	GO:0001678	intracellular glucose homeostasis	CARTPT	IDA		Human	PMID:11711504
Biological Process	GO:0032099	negative regulation of appetite	Cartpt	IMP		Mouse	MGI:MGI:1203479|PMID:9590691
Biological Process	GO:0032099	negative regulation of appetite	Cartpt	IDA		Rat	PMID:9590691|RGD:8554847
Biological Process	GO:0045779	negative regulation of bone resorption	CARTPT	IMP		Human	PMID:16614075
Biological Process	GO:0045779	negative regulation of bone resorption	Cartpt	IGI	UniProtKB:P56450	Mouse	MGI:MGI:3696590|PMID:16614075
Biological Process	GO:0070093	negative regulation of glucagon secretion	Cartpt	IDA		Rat	PMID:16443761|RGD:2313632
Biological Process	GO:0045777	positive regulation of blood pressure	CARTPT	IDA		Human	PMID:11711504
Biological Process	GO:0032812	positive regulation of epinephrine secretion	CARTPT	IDA		Human	PMID:11711504
Biological Process	GO:0043410	positive regulation of MAPK cascade	Cartpt	IDA		Mouse	MGI:MGI:3696614|PMID:15908120
Biological Process	GO:0043410	positive regulation of MAPK cascade	Cartpt	IDA		Rat	PMID:15908120|RGD:8554672
Biological Process	GO:0045860	positive regulation of protein kinase activity	Cartpt	IDA		Mouse	MGI:MGI:3696614|PMID:15908120
Biological Process	GO:0045860	positive regulation of protein kinase activity	Cartpt	IDA		Rat	PMID:15908120|RGD:8554672
Biological Process	GO:0051971	positive regulation of transmission of nerve impulse	CARTPT	IDA		Human	PMID:11711504
Biological Process	GO:0046850	regulation of bone remodeling	Cartpt	IMP	MGI:MGI:3576858	Mouse	PMID:15724149
Biological Process	GO:0050796	regulation of insulin secretion	Cartpt	IDA		Rat	PMID:16443761|RGD:2313632
Biological Process	GO:0070253	somatostatin secretion	Cartpt	IDA		Rat	PMID:16443761|RGD:2313632

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern