Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CARMIL2
  • Mouse genes Carmil2
  • Rat genes Carmil2
  • Zfish genes carmil2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Carmil2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005543	phospholipid binding	CARMIL2	IDA		Human	PMID:26578515
Molecular Function	GO:0005515	protein binding	Carmil2	IPI	PR:P47753	Mouse	PMID:23793062
Molecular Function	GO:0044877	protein-containing complex binding	CARMIL2	IDA		Human	PMID:26466680
Cellular Component	GO:0015629	actin cytoskeleton	CARMIL2	IDA		Human	PMID:26578515
Cellular Component	GO:0031252	cell leading edge	CARMIL2	IDA		Human	PMID:26466680
Cellular Component	GO:0005911	cell-cell junction	Carmil2	IDA		Mouse	PMID:23793062
Cellular Component	GO:0005737	cytoplasm	CARMIL2	IDA		Human	PMID:19846667
Cellular Component	GO:0005737	cytoplasm	CARMIL2	IDA		Human	PMID:26466680
Cellular Component	GO:0005737	cytoplasm	Carmil2	IDA		Mouse	PMID:23793062
Cellular Component	GO:0008290	F-actin capping protein complex	Carmil2	IDA		Mouse	PMID:23793062
Cellular Component	GO:0001772	immunological synapse	Carmil2	IDA		Mouse	PMID:23793062
Cellular Component	GO:0045111	intermediate filament cytoskeleton	CARMIL2	IDA		Human	PMID:19846667
Cellular Component	GO:0045111	intermediate filament cytoskeleton	CARMIL2	IDA		Human	PMID:26466680
Cellular Component	GO:0045111	intermediate filament cytoskeleton	CARMIL2	IDA		Human	PMID:26578515
Cellular Component	GO:0030027	lamellipodium	CARMIL2	IDA		Human	PMID:26578515
Cellular Component	GO:0044354	macropinosome	CARMIL2	IDA		Human	PMID:26578515
Cellular Component	GO:0016020	membrane	CARMIL2	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	CARMIL2	IDA		Human	PMID:26578515
Cellular Component	GO:0001726	ruffle	CARMIL2	IDA		Human	PMID:26466680
Cellular Component	GO:0001726	ruffle	CARMIL2	IDA		Human	PMID:26578515
Biological Process	GO:0051639	actin filament network formation	CARMIL2	IDA		Human	PMID:26466680
Biological Process	GO:0051639	actin filament network formation	CARMIL2	IDA		Human	PMID:26578515
Biological Process	GO:0045184	establishment of protein localization	Carmil2	IMP	MGI:MGI:5547539	Mouse	PMID:23793062
Biological Process	GO:0007163	establishment or maintenance of cell polarity	CARMIL2	IDA		Human	PMID:19846667
Biological Process	GO:0061339	establishment or maintenance of monopolar cell polarity	CARMIL2	IDA		Human	PMID:26466680
Biological Process	GO:0061339	establishment or maintenance of monopolar cell polarity	CARMIL2	IDA		Human	PMID:26578515
Biological Process	GO:0048872	homeostasis of number of cells	Carmil2	IMP	MGI:MGI:5547539	Mouse	PMID:23793062
Biological Process	GO:2000813	negative regulation of barbed-end actin filament capping	CARMIL2	IDA		Human	PMID:26466680
Biological Process	GO:0030335	positive regulation of cell migration	CARMIL2	IDA		Human	PMID:19846667
Biological Process	GO:0030335	positive regulation of cell migration	CARMIL2	IDA		Human	PMID:26466680
Biological Process	GO:0030335	positive regulation of cell migration	CARMIL2	IDA		Human	PMID:26578515
Biological Process	GO:0090091	positive regulation of extracellular matrix disassembly	CARMIL2	IDA		Human	PMID:26466680
Biological Process	GO:0090091	positive regulation of extracellular matrix disassembly	CARMIL2	IDA		Human	PMID:26578515
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Carmil2	IMP	MGI:MGI:5547539	Mouse	PMID:24097820
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Carmil2	IMP	MGI:MGI:4462559	Mouse	PMID:24097820
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	CARMIL2	IDA		Human	PMID:26466680
Biological Process	GO:1902745	positive regulation of lamellipodium organization	CARMIL2	IDA		Human	PMID:26578515
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Carmil2	IMP	MGI:MGI:5547539	Mouse	PMID:23793062
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Carmil2	IMP	MGI:MGI:4462559	Mouse	PMID:23793062
Biological Process	GO:1900029	positive regulation of ruffle assembly	CARMIL2	IDA		Human	PMID:26466680
Biological Process	GO:1900029	positive regulation of ruffle assembly	CARMIL2	IDA		Human	PMID:26578515
Biological Process	GO:0042102	positive regulation of T cell proliferation	Carmil2	IMP	MGI:MGI:5547539	Mouse	PMID:23793062
Biological Process	GO:0032729	positive regulation of type II interferon production	Carmil2	IMP	MGI:MGI:5547539	Mouse	PMID:23793062
Biological Process	GO:0050852	T cell receptor signaling pathway	Carmil2	IMP	MGI:MGI:5547539	Mouse	PMID:23793062
Biological Process	GO:0048538	thymus development	Carmil2	IMP	MGI:MGI:5547539	Mouse	PMID:23793062
Biological Process	GO:0044319	wound healing, spreading of cells	CARMIL2	IDA		Human	PMID:26466680
Biological Process	GO:0044319	wound healing, spreading of cells	CARMIL2	IDA		Human	PMID:26578515

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern