Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CARD9
  • Mouse genes Card9
  • Rat genes Card9
  • Zfish genes card9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Card9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050700	CARD domain binding	CARD9	IPI	UniProtKB:O95999	Human	PMID:11053425
Molecular Function	GO:0050700	CARD domain binding	CARD9	IPI	UniProtKB:O95999	Human	PMID:26488816
Molecular Function	GO:0050700	CARD domain binding	CARD9	IPI	UniProtKB:O95999	Human	PMID:31296852
Molecular Function	GO:0050700	CARD domain binding	Card9	IPI	UniProtKB:Q9Z0H7	Mouse	MGI:MGI:5310700|PMID:22265677
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:O95999	Human	PMID:22267217
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:A8K932	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:O14639	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:O60573	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:O75558	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:O95999	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P08727	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P15622-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P25800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P40425	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P55081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P56279	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P60370	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P63165	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q13829	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q14134	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q14D33	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q2TBE0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q3B820	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q53TS8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q548N1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q5VWN6-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q6NT76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q6NYC8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q6P1W5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q7L273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q7Z3I7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q7Z6G3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8IWZ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8IXK0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8IYA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8IYX8-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8N3Z6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8N720	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8N8B7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8NHQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8TAU3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q8TD31-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q96BZ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q96GN5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q96PV4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q96SQ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q99598	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9H2G9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9H5Z6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9P286	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9UER7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9UII6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9Y247	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9Y2D8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9Y2J4-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9Y4E8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q96GN5	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P08727	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:P36406	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q08117	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q3B820	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q6NYC8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q7Z3I7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9P286	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CARD9	IPI	UniProtKB:Q9Y4E8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Card9	IPI	PR:Q8K3Z0	Mouse	PMID:17187069
Molecular Function	GO:0019904	protein domain specific binding	Card9	IMP		Rat	PMID:11053425|RGD:1299399
Molecular Function	GO:0042803	protein homodimerization activity	CARD9	IPI	UniProtKB:Q9H257	Human	PMID:11053425
Molecular Function	GO:0043621	protein self-association	CARD9	IDA		Human	PMID:31296852
Cellular Component	GO:0032449	CBM complex	Card9	IDA		Mouse	MGI:MGI:5310700|PMID:22265677
Cellular Component	GO:0005737	cytoplasm	CARD9	IDA		Human	PMID:26488816
Cellular Component	GO:0005737	cytoplasm	CARD9	IDA		Human	PMID:11053425
Cellular Component	GO:0032991	protein-containing complex	CARD9	IDA		Human	PMID:22267217
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IMP		Human	PMID:24231284
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IMP		Human	PMID:25057046
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IMP		Human	PMID:25702837
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IDA		Human	PMID:26488816
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IMP		Human	PMID:26679537
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IMP		Human	PMID:26961233
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IMP		Human	PMID:29080677
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IMP		Human	PMID:33548172
Biological Process	GO:0061760	antifungal innate immune response	CARD9	IMP		Human	PMID:33558980
Biological Process	GO:0061760	antifungal innate immune response	Card9	IMP		Mouse	MGI:MGI:6508474|PMID:33548172
Biological Process	GO:0061760	antifungal innate immune response	Card9	IMP		Mouse	MGI:MGI:6117948|PMID:29080677
Biological Process	GO:0061760	antifungal innate immune response	Card9	IMP		Mouse	MGI:MGI:5919639|PMID:25621893
Biological Process	GO:0061760	antifungal innate immune response	Card9	IMP		Mouse	MGI:MGI:6445005|PMID:32358020
Biological Process	GO:0061760	antifungal innate immune response	Card9	IDA		Mouse	MGI:MGI:5310700|PMID:22265677
Biological Process	GO:0061760	antifungal innate immune response	Card9	IMP		Mouse	MGI:MGI:5567862|PMID:24470469
Biological Process	GO:0061760	antifungal innate immune response	Card9	IMP		Mouse	MGI:MGI:5919121|PMID:26679537
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0051607	defense response to virus	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0048874	host-mediated regulation of intestinal microbiota composition	CARD9	IMP		Human	PMID:33548172
Biological Process	GO:0048874	host-mediated regulation of intestinal microbiota composition	Card9	IMP		Mouse	MGI:MGI:5829544|PMID:27158904
Biological Process	GO:0048874	host-mediated regulation of intestinal microbiota composition	Card9	IMP		Mouse	MGI:MGI:6694416|PMID:23732773
Biological Process	GO:0048874	host-mediated regulation of intestinal microbiota composition	Card9	IMP		Mouse	MGI:MGI:6508474|PMID:33548172
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Card9	IMP		Rat	PMID:11053425|RGD:1299399
Biological Process	GO:0016064	immunoglobulin mediated immune response	CARD9	IMP		Human	PMID:33548172
Biological Process	GO:0016064	immunoglobulin mediated immune response	Card9	IMP		Mouse	MGI:MGI:6508474|PMID:33548172
Biological Process	GO:0032635	interleukin-6 production	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0007254	JNK cascade	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0010934	macrophage cytokine production	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0002446	neutrophil mediated immunity	CARD9	IMP		Human	PMID:26679537
Biological Process	GO:0002446	neutrophil mediated immunity	Card9	IMP		Mouse	MGI:MGI:5919121|PMID:26679537
Biological Process	GO:0002446	neutrophil mediated immunity	Card9	IMP		Mouse	MGI:MGI:5919639|PMID:25621893
Biological Process	GO:0032722	positive regulation of chemokine production	Card9	IMP		Mouse	MGI:MGI:5919639|PMID:25621893
Biological Process	GO:0032722	positive regulation of chemokine production	Card9	IMP		Mouse	MGI:MGI:5567862|PMID:24470469
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	CARD9	IMP		Human	PMID:22267217
Biological Process	GO:0001819	positive regulation of cytokine production	CARD9	IMP		Human	PMID:24231284
Biological Process	GO:0001819	positive regulation of cytokine production	CARD9	IMP		Human	PMID:25057046
Biological Process	GO:0001819	positive regulation of cytokine production	Card9	IDA		Mouse	MGI:MGI:5310700|PMID:22265677
Biological Process	GO:0001819	positive regulation of cytokine production	Card9	IMP		Mouse	MGI:MGI:5919121|PMID:26679537
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	Card9	IMP		Mouse	MGI:MGI:5618187|PMID:25267792
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Card9	IMP		Mouse	MGI:MGI:5618187|PMID:25267792
Biological Process	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	CARD9	IMP		Human	PMID:26961233
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	CARD9	IEP		Human	PMID:11053425
Biological Process	GO:0045089	positive regulation of innate immune response	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0032740	positive regulation of interleukin-17 production	CARD9	IMP		Human	PMID:26961233
Biological Process	GO:0032755	positive regulation of interleukin-6 production	CARD9	IMP		Human	PMID:25702837
Biological Process	GO:0032755	positive regulation of interleukin-6 production	CARD9	IMP		Human	PMID:26679537
Biological Process	GO:0032755	positive regulation of interleukin-6 production	CARD9	IMP		Human	PMID:26961233
Biological Process	GO:0032755	positive regulation of interleukin-6 production	CARD9	IMP		Human	PMID:29080677
Biological Process	GO:0032755	positive regulation of interleukin-6 production	CARD9	IMP		Human	PMID:33558980
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0046330	positive regulation of JNK cascade	CARD9	IDA		Human	PMID:17187069
Biological Process	GO:0046330	positive regulation of JNK cascade	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CARD9	IMP		Human	PMID:25057046
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CARD9	IMP		Human	PMID:25702837
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CARD9	IDA		Human	PMID:26488816
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CARD9	IMP		Human	PMID:29080677
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CARD9	IDA		Human	PMID:31296852
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CARD9	IMP		Human	PMID:33558980
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Card9	IMP		Mouse	MGI:MGI:6117948|PMID:29080677
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Card9	IDA		Mouse	MGI:MGI:5310700|PMID:22265677
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	CARD9	IDA		Human	PMID:17187069
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	Card9	IMP		Mouse	MGI:MGI:6117948|PMID:29080677
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	CARD9	IMP		Human	PMID:24231284
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	CARD9	IMP		Human	PMID:29080677
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	Card9	IMP		Mouse	MGI:MGI:5567862|PMID:24470469
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	Card9	IMP		Mouse	MGI:MGI:6445005|PMID:32358020
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0051260	protein homooligomerization	CARD9	IDA		Human	PMID:31296852
Biological Process	GO:0032663	regulation of interleukin-2 production	Card9	IMP	MGI:MGI:3663486	Mouse	PMID:16862125
Biological Process	GO:0032675	regulation of interleukin-6 production	Card9	IMP	MGI:MGI:3663486	Mouse	PMID:16862125
Biological Process	GO:0032680	regulation of tumor necrosis factor production	Card9	IMP	MGI:MGI:3663486	Mouse	PMID:16862125
Biological Process	GO:0043330	response to exogenous dsRNA	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0009620	response to fungus	Card9	IMP	MGI:MGI:3663486	Mouse	PMID:16862125
Biological Process	GO:0032495	response to muramyl dipeptide	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0032494	response to peptidoglycan	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0009410	response to xenobiotic stimulus	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0051403	stress-activated MAPK cascade	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069
Biological Process	GO:0032640	tumor necrosis factor production	Card9	IMP	MGI:MGI:3698412	Mouse	PMID:17187069

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern