Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CAMK2N1
  • Mouse genes Camk2n1
  • Rat genes Camk2n1
  • Zfish genes camk2n1,camk2n1a,camk2n1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Camk2n1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008427	calcium-dependent protein kinase inhibitor activity	Camk2n1	IDA		Rat	PMID:11182241|RGD:1299437
Molecular Function	GO:0019901	protein kinase binding	Camk2n1	IDA		Rat	PMID:11182241|RGD:1299437
Molecular Function	GO:0019901	protein kinase binding	Camk2n1	IPI	RGD:2261	Rat	PMID:11182241|RGD:1299437
Molecular Function	GO:0019901	protein kinase binding	camk2n1a	IPI	ZFIN:ZDB-GENE-051113-72	Zfish	PMID:20925123
Molecular Function	GO:0004860	protein kinase inhibitor activity	Camk2n1	IDA		Mouse	PMID:17350603
Cellular Component	GO:0030425	dendrite	Camk2n1	IDA		Rat	PMID:11182241|RGD:1299437
Cellular Component	GO:0043025	neuronal cell body	Camk2n1	IDA		Rat	PMID:11182241|RGD:1299437
Cellular Component	GO:0014069	postsynaptic density	Camk2n1	IDA		Mouse	PMID:17350603
Cellular Component	GO:0045202	synapse	Camk2n1	IDA		Mouse	MGI:MGI:6827206|PMID:28642476
Cellular Component	GO:0045202	synapse	Camk2n1	IDA		Mouse	PMID:17350603
Biological Process	GO:0055074	calcium ion homeostasis	Camk2n1	IMP		Rat	PMID:31327268|RGD:18899561
Biological Process	GO:0007616	long-term memory	Camk2n1	IMP		Mouse	MGI:MGI:6827206|PMID:28642476
Biological Process	GO:0006469	negative regulation of protein kinase activity	camk2n1a	IDA		Zfish	PMID:20925123
Biological Process	GO:0001933	negative regulation of protein phosphorylation	camk2n1a	IDA		Zfish	PMID:20925123
Biological Process	GO:0050729	positive regulation of inflammatory response	Camk2n1	IDA		Mouse	MGI:MGI:6750967|PMID:33746041
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Camk2n1	IMP		Rat	PMID:31327268|RGD:18899561
Biological Process	GO:0003084	positive regulation of systemic arterial blood pressure	Camk2n1	IMP		Rat	PMID:31327268|RGD:18899561

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern