Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CALD1
  • Mouse genes Cald1
  • Rat genes Cald1
  • Zfish genes cald1a,cald1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cald1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Cald1	IDA		Rat	PMID:3384851|RGD:2303065
Molecular Function	GO:0003779	actin binding	cald1b	IDA		Zfish	PMID:20591105
Molecular Function	GO:0045296	cadherin binding	CALD1	HDA		Human	PMID:25468996
Molecular Function	GO:0032036	myosin heavy chain binding	cald1b	IDA		Zfish	PMID:20591105
Molecular Function	GO:0005515	protein binding	CALD1	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Cellular Component	GO:0030478	actin cap	Cald1	IDA		Mouse	PMID:2909534
Cellular Component	GO:0015629	actin cytoskeleton	CALD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005884	actin filament	Cald1	IDA		Rat	PMID:3384851|RGD:2303065
Cellular Component	GO:0030425	dendrite	Cald1	IDA		Rat	PMID:7493632|RGD:2303066
Cellular Component	GO:0043197	dendritic spine	Cald1	IDA		Rat	PMID:11134639|RGD:2303067
Cellular Component	GO:0043197	dendritic spine	Cald1	IDA		Rat	PMID:18582438|RGD:2303068
Cellular Component	GO:0098978	glutamatergic synapse	Cald1	IDA		Rat	PMID:11134639|RGD:2303067
Cellular Component	GO:0016020	membrane	Cald1	IDA		Mouse	PMID:2909534
Cellular Component	GO:0043025	neuronal cell body	Cald1	IDA		Rat	PMID:7493632|RGD:2303066
Cellular Component	GO:0005886	plasma membrane	CALD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098794	postsynapse	Cald1	IDA		Rat	PMID:11134639|RGD:2303067
Cellular Component	GO:0014069	postsynaptic density	Cald1	IDA		Rat	PMID:11134639|RGD:2303067
Cellular Component	GO:0014069	postsynaptic density	Cald1	IDA		Rat	PMID:18582438|RGD:2303068
Biological Process	GO:0051017	actin filament bundle assembly	Cald1	IDA		Rat	PMID:3384851|RGD:2303065
Biological Process	GO:0001525	angiogenesis	cald1b	IMP	ZFIN:ZDB-MRPHLNO-090413-1	Zfish	PMID:18980955
Biological Process	GO:0043534	blood vessel endothelial cell migration	cald1b	IMP	ZFIN:ZDB-MRPHLNO-090413-1	Zfish	PMID:18980955
Biological Process	GO:0001947	heart looping	cald1b	IMP	ZFIN:ZDB-MRPHLNO-090413-2	Zfish	PMID:19000902
Biological Process	GO:0001947	heart looping	cald1b	IMP	ZFIN:ZDB-MRPHLNO-090413-1	Zfish	PMID:19000902
Biological Process	GO:0003007	heart morphogenesis	cald1b	IMP	ZFIN:ZDB-MRPHLNO-090413-1	Zfish	PMID:19000902
Biological Process	GO:0003007	heart morphogenesis	cald1b	IMP	ZFIN:ZDB-MRPHLNO-090413-2	Zfish	PMID:19000902
Biological Process	GO:0030432	peristalsis	cald1a	IMP	ZFIN:ZDB-MRPHLNO-121022-1	Zfish	PMID:22316291
Biological Process	GO:0032092	positive regulation of protein binding	Cald1	IDA		Rat	PMID:3384851|RGD:2303065
Biological Process	GO:0001570	vasculogenesis	cald1b	IMP	ZFIN:ZDB-MRPHLNO-090413-1	Zfish	PMID:18980955

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern