Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CAD
  • Mouse genes Cad
  • Rat genes Cad
  • Zfish genes cad
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cad

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004070	aspartate carbamoyltransferase activity	Cad	IDA		Mouse	PMID:5125237
Molecular Function	GO:0004070	aspartate carbamoyltransferase activity	Cad	IDA		Rat	PMID:1148171|RGD:2303536
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	Cad	IMP		Mouse	PMID:33771897
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	Cad	IDA		Mouse	PMID:5125237
Molecular Function	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	Cad	IDA		Rat	PMID:1148171|RGD:2303536
Molecular Function	GO:0004151	dihydroorotase activity	CAD	IDA		Human	PMID:24332717
Molecular Function	GO:0004151	dihydroorotase activity	Cad	IMP		Mouse	PMID:33771897
Molecular Function	GO:0004151	dihydroorotase activity	Cad	IDA		Rat	PMID:1148171|RGD:2303536
Molecular Function	GO:0019899	enzyme binding	CAD	IPI	UniProtKB:Q99638	Human	PMID:15326225
Molecular Function	GO:0042802	identical protein binding	CAD	IPI	UniProtKB:P27708	Human	PMID:24332717
Molecular Function	GO:0042802	identical protein binding	Cad	IDA		Rat	PMID:26565|RGD:2303534
Molecular Function	GO:0036094	small molecule binding	CAD	EXP		Human	PMID:27265852
Molecular Function	GO:0008270	zinc ion binding	CAD	IDA		Human	PMID:24332717
Cellular Component	GO:0042995	cell projection	Cad	IDA		Rat	PMID:1673139|RGD:5132585
Cellular Component	GO:0005829	cytosol	CAD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	CAD	IDA		Human	PMID:15890648
Cellular Component	GO:0005829	cytosol	Cad	IDA		Rat	PMID:2803258|RGD:10755425
Cellular Component	GO:0070062	extracellular exosome	CAD	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	CAD	HDA		Human	PMID:19946888
Cellular Component	GO:0043025	neuronal cell body	Cad	IDA		Rat	PMID:1673139|RGD:5132585
Cellular Component	GO:0016363	nuclear matrix	CAD	IDA		Human	PMID:9525610
Cellular Component	GO:0005634	nucleus	CAD	IDA		Human	PMID:15890648
Cellular Component	GO:0032991	protein-containing complex	Cad	IDA		Rat	PMID:26565|RGD:2303534
Cellular Component	GO:0043195	terminal bouton	Cad	IDA		Rat	PMID:1673139|RGD:5132585
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	CAD	IDA		Human	PMID:24332717
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	Cad	IDA		Rat	PMID:1476792|RGD:5132591
Biological Process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	cad	IMP	ZFIN:ZDB-GENO-010731-7	Zfish	PMID:15937129
Biological Process	GO:0044205	'de novo' UMP biosynthetic process	CAD	IDA		Human	PMID:25678555
Biological Process	GO:0044205	'de novo' UMP biosynthetic process	Cad	IMP		Mouse	PMID:33771897
Biological Process	GO:0031100	animal organ regeneration	Cad	IEP		Rat	PMID:13671431|RGD:2303539
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Cad	IEP		Rat	PMID:10659854|RGD:2303528
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Cad	IEP		Rat	PMID:8548770|RGD:5132280
Biological Process	GO:0019240	citrulline biosynthetic process	Cad	IDA		Rat	PMID:7053379|RGD:10755426
Biological Process	GO:0021610	facial nerve morphogenesis	cad	IMP	ZFIN:ZDB-GENO-151106-3	Zfish	PMID:24280100
Biological Process	GO:0007565	female pregnancy	Cad	IEP		Rat	PMID:6020217|RGD:2303605
Biological Process	GO:0021615	glossopharyngeal nerve morphogenesis	cad	IMP	ZFIN:ZDB-GENO-151106-3	Zfish	PMID:24280100
Biological Process	GO:0006541	glutamine metabolic process	Cad	IEP		Rat	PMID:2474281|RGD:5132588
Biological Process	GO:0006541	glutamine metabolic process	Cad	IDA		Rat	PMID:2803258|RGD:10755425
Biological Process	GO:0007507	heart development	Cad	IEP		Rat	PMID:14160653|RGD:2303538
Biological Process	GO:0007595	lactation	Cad	IEP		Rat	PMID:1476792|RGD:5132591
Biological Process	GO:0001889	liver development	Cad	IEP		Rat	PMID:14160653|RGD:2303538
Biological Process	GO:0001946	lymphangiogenesis	cad	IMP	ZFIN:ZDB-GENO-150506-3	Zfish	PMID:25294789
Biological Process	GO:0048812	neuron projection morphogenesis	cad	IMP	ZFIN:ZDB-GENO-151106-3	Zfish	PMID:24280100
Biological Process	GO:0008593	regulation of Notch signaling pathway	cad	IMP	ZFIN:ZDB-GENO-150506-3	Zfish	PMID:25294789
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	cad	IGI	ZFIN:ZDB-GENO-150506-3,ZFIN:ZDB-MRPHLNO-100205-4	Zfish	PMID:25294789
Biological Process	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	cad	IGI	ZFIN:ZDB-GENO-150506-3,ZFIN:ZDB-MRPHLNO-051212-2	Zfish	PMID:25294789
Biological Process	GO:0014075	response to amine	Cad	IEP		Rat	PMID:2864015|RGD:2303531
Biological Process	GO:0031000	response to caffeine	Cad	IEP		Rat	PMID:6149265|RGD:2303533
Biological Process	GO:0051414	response to cortisol	Cad	IEP		Rat	PMID:2353918|RGD:2303529
Biological Process	GO:0032868	response to insulin	Cad	IDA		Rat	PMID:3311028|RGD:10755428
Biological Process	GO:0042594	response to starvation	Cad	IDA		Rat	PMID:3311028|RGD:10755428
Biological Process	GO:0033574	response to testosterone	Cad	IEP		Rat	PMID:6030068|RGD:2303540
Biological Process	GO:0060041	retina development in camera-type eye	cad	IMP	ZFIN:ZDB-GENO-010731-7	Zfish	PMID:11476583
Biological Process	GO:0021636	trigeminal nerve morphogenesis	cad	IMP	ZFIN:ZDB-GENO-151106-3	Zfish	PMID:24280100
Biological Process	GO:0006225	UDP biosynthetic process	CAD	IDA		Human	PMID:25678555
Biological Process	GO:0006228	UTP biosynthetic process	Cad	IDA		Rat	PMID:10659854|RGD:2303528
Biological Process	GO:0021644	vagus nerve morphogenesis	cad	IMP	ZFIN:ZDB-GENO-151106-3	Zfish	PMID:24280100
Biological Process	GO:0006805	xenobiotic metabolic process	Cad	IMP		Rat	PMID:18515330|RGD:2303526

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern