Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CACNG4
  • Mouse genes Cacng4
  • Rat genes Cacng4
  • Zfish genes cacng4a,cacng4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacng4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005246	calcium channel regulator activity	CACNG4	IDA		Human	PMID:21127204
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Cacng4	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Cacng4	IDA		Mouse	PMID:22632720
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Cacng4	IDA		Rat	PMID:19265014|RGD:8554136
Cellular Component	GO:0044297	cell body	Cacng4	IDA		Rat	PMID:23751177|RGD:13524561
Cellular Component	GO:0009986	cell surface	Cacng4	IDA		Rat	PMID:21276808|RGD:13524552
Cellular Component	GO:0098978	glutamatergic synapse	Cacng4	IDA		Mouse	PMID:17880893
Cellular Component	GO:0098978	glutamatergic synapse	Cacng4	IMP		Mouse	PMID:17880893
Cellular Component	GO:0098978	glutamatergic synapse	Cacng4	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:1990454	L-type voltage-gated calcium channel complex	CACNG4	IDA		Human	PMID:21127204
Cellular Component	GO:0014069	postsynaptic density	Cacng4	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng4	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng4	IDA		Rat	PMID:21276808|RGD:13524552
Cellular Component	GO:0036477	somatodendritic compartment	Cacng4	IDA		Mouse	MGI:MGI:3794899|PMID:18341993
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	Cacng4	IDA		Rat	PMID:12771129|RGD:13515082
Biological Process	GO:2000311	regulation of AMPA receptor activity	CACNG4	IDA		Human	PMID:21172611
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng4	IMP		Mouse	MGI:MGI:5284772|PMID:17880894
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng4	IDA		Rat	PMID:17880894|RGD:8553817
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng4	IDA		Rat	PMID:19234459|RGD:8554069
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Cacng4	IMP		Mouse	PMID:17880893
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	Cacng4	IDA		Mouse	PMID:17880893
Biological Process	GO:0042220	response to cocaine	Cacng4	IDA		Rat	PMID:21276808|RGD:13524552
Biological Process	GO:0019226	transmission of nerve impulse	Cacng4	IGI	MGI:MGI:1316660	Mouse	PMID:15677329

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern