Cacng4
Gene Detail

Symbol Name ID

Cacng4 calcium channel, voltage-dependent, gamma subunit 4 MGI:1859167

Feature Type

protein coding gene

Genetic Map

Chromosome 11

70.29 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr11:107732357-107794557 bp, - strand From VEGA annotation of GRCm38   62201 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Cacng4 ± 2 cM)

Gene Tree: Cacng4

Human ortholog

CACNG4 calcium channel, voltage-dependent, gamma subunit 4 NCBI Gene ID 27092
Human Chr17:64961013-65029518 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(4) : Targeted(4)
 

Homozygous mutant mice are viable, fertile and phenotypically normal with no ataxic gait or absence seizures.

 

Gene Ontology (GO) classifications

All GO classifications: (22 annotations)

Process	calcium ion transmembrane transport, calcium ion transport, ...
Component	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, integral to membrane, ...
Function	calcium channel activity, ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (346)    Tissues (121)    Images (91)
Theiler Stages: 17, 19, 20, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	205
In situ reporter (knock in)	90
Northern blot	3
RT-PCR	48

cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) Genomic(1) cDNA(6) Primer pair(3)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000003107 (Evidence)
Ensembl Gene Model	ENSMUSG00000020723 (Evidence)
Entrez Gene	54377 (Evidence)
DFCI	TC1602301, TC1639489
DoTS	DT.101146564, DT.101718586, DT.87068544
NIA Mouse Gene Index	U033561
Consensus CDS Project	CCDS25571.1
International Mouse Knockout Project Status	Cacng4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000003107	VEGA Gene Model | MGI Sequence Detail	62201	C57BL/6J
transcript	OTTMUST00000006397	VEGA | MGI Sequence Detail	3500	Not Applicable
polypeptide	OTTMUSP00000003012	VEGA | MGI Sequence Detail	327	Not Applicable

All sequences(27) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(284 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004031	PMP-22/EMP/MP20/Claudin
InterPro	IPR005423	Voltage-dependent calcium channel, gamma-4 subunit
InterPro	IPR008368	Voltage-dependent calcium channel, gamma subunit
Protein Ontology	PR:000004953	voltage-dependent calcium channel gamma-4 subunit

References

(Earliest) J:61749 Burgess DL, et al., Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome Res. 1999 Dec;9(12):1204-13
(Latest) J:188364 Schwenk J, et al., High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron. 2012 May 24;74(4):621-33
All references(38)

Other accession IDs

MGI:2144142, MGI:2144541