Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C3AR1
  • Mouse genes C3ar1
  • Rat genes C3ar1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set C3ar1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001850	complement component C3a binding	C3ar1	IDA		Rat	PMID:15292245|RGD:2303020
Molecular Function	GO:0001850	complement component C3a binding	C3ar1	IDA		Rat	PMID:9464274|RGD:724614
Molecular Function	GO:0004876	complement component C3a receptor activity	C3AR1	IDA		Human	PMID:10571060
Molecular Function	GO:0004876	complement component C3a receptor activity	C3ar1	IDA		Rat	PMID:15292245|RGD:2303020
Molecular Function	GO:0004876	complement component C3a receptor activity	C3ar1	IDA		Rat	PMID:9464274|RGD:724614
Molecular Function	GO:0004876	complement component C3a receptor activity	C3ar1	IPI	RGD:2232	Rat	PMID:9464274|RGD:724614
Molecular Function	GO:0004930	G protein-coupled receptor activity	C3AR1	IPI	UniProtKB:P30678	Human	PMID:10571060
Molecular Function	GO:0004930	G protein-coupled receptor activity	C3AR1	IPI	UniProtKB:P30679	Human	PMID:10571060
Molecular Function	GO:0004930	G protein-coupled receptor activity	C3AR1	IPI	UniProtKB:Q9TU29	Human	PMID:10571060
Cellular Component	GO:0005886	plasma membrane	C3ar1	IDA		Rat	PMID:15292245|RGD:2303020
Biological Process	GO:0002430	complement receptor mediated signaling pathway	C3AR1	IDA		Human	PMID:10571060
Biological Process	GO:0045766	positive regulation of angiogenesis	C3ar1	IMP		Mouse	MGI:MGI:3617287|PMID:16452172
Biological Process	GO:0030335	positive regulation of cell migration	C3ar1	IMP		Rat	PMID:18635264|RGD:5129699
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	C3ar1	IDA		Rat	PMID:15292245|RGD:2303020
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	C3AR1	IPI	UniProtKB:P30678	Human	PMID:10571060
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	C3AR1	IPI	UniProtKB:P30679	Human	PMID:10571060
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	C3AR1	IPI	UniProtKB:Q9TU29	Human	PMID:10571060
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	C3ar1	IMP		Rat	PMID:23713944|RGD:7411623
Biological Process	GO:0072126	positive regulation of glomerular mesangial cell proliferation	C3ar1	IMP		Rat	PMID:23713944|RGD:7411623
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	C3ar1	IMP		Mouse	MGI:MGI:3617287|PMID:16452172
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	C3ar1	IMP		Mouse	MGI:MGI:3617287|PMID:16452172
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	C3ar1	IMP		Rat	PMID:22089112|RGD:7411627
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	C3ar1	IMP		Mouse	MGI:MGI:3617287|PMID:16452172
Biological Process	GO:0008217	regulation of blood pressure	C3ar1	IDA		Rat	PMID:19285573|RGD:5129696
Biological Process	GO:0002462	tolerance induction to nonself antigen	C3ar1	IMP		Rat	PMID:12514742|RGD:5129547

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern