Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BNIP3L
  • Mouse genes Bnip3l
  • Rat genes Bnip3l
  • Zfish genes bnip3la,bnip3lb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bnip3l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	BNIP3L	IPI	UniProtKB:O60238	Human	PMID:10381623
Molecular Function	GO:0042802	identical protein binding	BNIP3L	IPI	UniProtKB:O60238	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	BNIP3L	IPI	UniProtKB:O60238	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	BNIP3L	IPI	UniProtKB:O60238	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	BNIP3L	IPI	UniProtKB:O60238	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	Bnip3l	IPI	PR:Q9Z2F7	Mouse	PMID:9867803
Molecular Function	GO:0005521	lamin binding	BNIP3L	IDA		Human	PMID:10381623
Molecular Function	GO:0005521	lamin binding	BNIP3L	IPI	UniProtKB:P02545-2	Human	PMID:10381623
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P03247	Human	PMID:10381623
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12982	Human	PMID:10381623
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:10381623
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P17152	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9H492	Human	PMID:20010802
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:O75143	Human	PMID:20200478
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:O95166	Human	PMID:20200478
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P38182	Human	PMID:20200478
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9GZQ8	Human	PMID:20200478
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q8TC71	Human	PMID:21264221
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9BXN2	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9NRQ5	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9NQ11	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P22736-1	Human	PMID:24316735
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P17152	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q5T700	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q969F0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9BXN2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9NRQ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q15848	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P17152	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q5T700	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:O43169	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P17152	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P60520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q12983	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9BXN2-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9H0R8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9H2S6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9NRQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9NRS4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:A0A663DJA2	Human	PMID:34845370
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q9H492	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P03247	Human	PMID:9973195
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:P10415	Human	PMID:9973195
Molecular Function	GO:0005515	protein binding	BNIP3L	IPI	UniProtKB:Q92934	Human	PMID:9973195
Molecular Function	GO:0005515	protein binding	Bnip3l	IPI	UniProtKB:O75143|UniProtKB:O95166|UniProtKB:P60520|UniProtKB:Q9GZQ8|UniProtKB:Q9H0R8	Mouse	MGI:MGI:5616312|PMID:20200478
Molecular Function	GO:0005515	protein binding	Bnip3l	IPI	UniProtKB:Q69ZI1	Mouse	MGI:MGI:3828389|PMID:17095503
Molecular Function	GO:0005515	protein binding	Bnip3l	IPI	UniProtKB:O95166|UniProtKB:P60520|UniProtKB:Q9GZQ8|UniProtKB:Q9H0R8|UniProtKB:Q9H492	Mouse	MGI:MGI:4887532|PMID:20010802
Molecular Function	GO:0005515	protein binding	Bnip3l	IPI	RGD:736805	Rat	PMID:19363302|RGD:7483576
Molecular Function	GO:0042803	protein homodimerization activity	BNIP3L	IDA		Human	PMID:10381623
Cellular Component	GO:0005829	cytosol	Bnip3l	IDA		Rat	PMID:15902200|RGD:2314138
Cellular Component	GO:0005783	endoplasmic reticulum	BNIP3L	IDA		Human	PMID:10381623
Cellular Component	GO:0005741	mitochondrial outer membrane	BNIP3L	IMP		Human	PMID:21264228
Cellular Component	GO:0005739	mitochondrion	BNIP3L	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	BNIP3L	IDA		Human	PMID:10381623
Cellular Component	GO:0005739	mitochondrion	BNIP3L	IDA		Human	PMID:9973195
Cellular Component	GO:0005739	mitochondrion	Bnip3l	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Bnip3l	IDA		Mouse	PMID:9867803
Cellular Component	GO:0005739	mitochondrion	Bnip3l	IDA		Mouse	PMID:23028046
Cellular Component	GO:0005739	mitochondrion	Bnip3l	IDA		Rat	PMID:15902200|RGD:2314138
Cellular Component	GO:0005635	nuclear envelope	BNIP3L	IDA		Human	PMID:10381623
Cellular Component	GO:0016607	nuclear speck	BNIP3L	IDA		Human	GO_REF:0000052
Biological Process	GO:0071456	cellular response to hypoxia	BNIP3L	IGI	UniProtKB:Q12983	Human	PMID:19273585
Biological Process	GO:0051607	defense response to virus	BNIP3L	IDA		Human	PMID:9973195
Biological Process	GO:0001947	heart looping	bnip3lb	IMP		Zfish	PMID:16854375
Biological Process	GO:0035694	mitochondrial protein catabolic process	BNIP3L	IMP		Human	PMID:21264228
Biological Process	GO:0043066	negative regulation of apoptotic process	BNIP3L	IDA		Human	PMID:10381623
Biological Process	GO:0060548	negative regulation of cell death	BNIP3L	IGI	UniProtKB:Q12983	Human	PMID:19273585
Biological Process	GO:0045822	negative regulation of heart contraction	bnip3lb	IMP		Zfish	PMID:16854375
Biological Process	GO:0010917	negative regulation of mitochondrial membrane potential	Bnip3l	IMP		Rat	PMID:26512955|RGD:11564338
Biological Process	GO:0043065	positive regulation of apoptotic process	BNIP3L	IDA		Human	PMID:9973195
Biological Process	GO:0043065	positive regulation of apoptotic process	Bnip3l	IDA		Mouse	PMID:9867803
Biological Process	GO:0043065	positive regulation of apoptotic process	Bnip3l	IMP		Rat	PMID:15695738|RGD:7483578
Biological Process	GO:0043065	positive regulation of apoptotic process	bnip3lb	IMP		Zfish	PMID:16854375
Biological Process	GO:0016239	positive regulation of macroautophagy	BNIP3L	IGI	UniProtKB:Q12983	Human	PMID:19273585
Biological Process	GO:0035794	positive regulation of mitochondrial membrane permeability	Bnip3l	IMP		Rat	PMID:26512955|RGD:11564338
Biological Process	GO:1903146	regulation of autophagy of mitochondrion	Bnip3l	IGI	UniProtKB:Q9Z2F7	Mouse	MGI:MGI:5616312|PMID:20200478
Biological Process	GO:1903214	regulation of protein targeting to mitochondrion	Bnip3l	IGI	UniProtKB:Q9Z2F7	Mouse	MGI:MGI:5616312|PMID:20200478

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern