Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP6AP2
  • Mouse genes Atp6ap2
  • Rat genes Atp6ap2
  • Zfish genes atp6ap2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp6ap2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:P00797	Human	PMID:12045255
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:O75581	Human	PMID:20093472
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:P27449	Human	PMID:20093472
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:P61421	Human	PMID:20093472
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q15904	Human	PMID:29127204
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q3ZAQ7	Human	PMID:29127204
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:P61421	Human	PMID:30374053
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q9P0T7	Human	PMID:30374053
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:O00526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:P21854	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:P42857	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:P53801	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q16617	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q5BJF2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q969S6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATP6AP2	IPI	UniProtKB:Q9NPL8	Human	PMID:32296183
Cellular Component	GO:0016324	apical plasma membrane	Atp6ap2	IDA		Rat	PMID:21321306|RGD:5132599
Cellular Component	GO:0044297	cell body	Atp6ap2	IDA		Rat	PMID:18326551|RGD:5132610
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ATP6AP2	IDA		Human	PMID:29127204
Cellular Component	GO:0010008	endosome membrane	Atp6ap2	IDA		Mouse	MGI:MGI:6467701|PMID:30985297
Cellular Component	GO:0009897	external side of plasma membrane	ATP6AP2	IDA		Human	PMID:12045255
Cellular Component	GO:0009897	external side of plasma membrane	ATP6AP2	IDA		Human	PMID:15746149
Cellular Component	GO:0070062	extracellular exosome	ATP6AP2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ATP6AP2	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	ATP6AP2	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Atp6ap2	IDA		Rat	PMID:21321306|RGD:5132599
Cellular Component	GO:0005765	lysosomal membrane	Atp6ap2	IDA		Mouse	MGI:MGI:6467701|PMID:30985297
Cellular Component	GO:0005764	lysosome	ATP6AP2	IDA		Human	PMID:29127204
Cellular Component	GO:0016020	membrane	ATP6AP2	IDA		Human	PMID:33065002
Cellular Component	GO:0043005	neuron projection	Atp6ap2	IDA		Rat	PMID:18326551|RGD:5132610
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp6ap2	EXP		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp6ap2	IDA		Rat	PMID:32165585|RGD:39458019
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	ATP6AP2	IMP		Human	PMID:29127204
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	ATP6AP2	IMP		Human	PMID:30985297
Biological Process	GO:0002003	angiotensin maturation	ATP6AP2	IDA		Human	PMID:12045255
Biological Process	GO:0002003	angiotensin maturation	ATP6AP2	IDA		Human	PMID:15746149
Biological Process	GO:0045176	apical protein localization	atp6ap2	IMP	ZFIN:ZDB-GENO-210929-1	Zfish	PMID:32328632
Biological Process	GO:0021626	central nervous system maturation	ATP6AP2	IMP		Human	PMID:30985297
Biological Process	GO:0021626	central nervous system maturation	Atp6ap2	IMP		Mouse	MGI:MGI:6467701|PMID:30985297
Biological Process	GO:0048069	eye pigmentation	ATP6AP2	IMP		Human	PMID:20093472
Biological Process	GO:0060323	head morphogenesis	ATP6AP2	IMP		Human	PMID:20093472
Biological Process	GO:0035622	intrahepatic bile duct development	atp6ap2	IMP	ZFIN:ZDB-MRPHLNO-120511-4	Zfish	PMID:22465374
Biological Process	GO:0035622	intrahepatic bile duct development	atp6ap2	IMP	ZFIN:ZDB-MRPHLNO-120511-5	Zfish	PMID:22465374
Biological Process	GO:0035622	intrahepatic bile duct development	atp6ap2	IMP	ZFIN:ZDB-MRPHLNO-120618-1	Zfish	PMID:22465374
Biological Process	GO:0035622	intrahepatic bile duct development	atp6ap2	IMP	ZFIN:ZDB-GENO-120209-19	Zfish	PMID:22465374
Biological Process	GO:0035622	intrahepatic bile duct development	atp6ap2	IGI	ZFIN:ZDB-GENE-050327-73	Zfish	PMID:22465374
Biological Process	GO:0007042	lysosomal lumen acidification	ATP6AP2	IMP		Human	PMID:32276428
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ATP6AP2	IMP		Human	PMID:30374053
Biological Process	GO:0032914	positive regulation of transforming growth factor beta1 production	ATP6AP2	IDA		Human	PMID:16374430
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	ATP6AP2	IMP		Human	PMID:20093472
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	Atp6ap2	IMP		Mouse	MGI:MGI:4421218|PMID:20093472
Biological Process	GO:0043408	regulation of MAPK cascade	ATP6AP2	IDA		Human	PMID:12045255
Biological Process	GO:0043408	regulation of MAPK cascade	ATP6AP2	IDA		Human	PMID:15746149
Biological Process	GO:0021903	rostrocaudal neural tube patterning	ATP6AP2	IMP		Human	PMID:20093472
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6ap2	IDA		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6ap2	EXP		Mouse	PMID:28793259
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Atp6ap2	IMP		Mouse	PMID:28793259

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern