Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATP12A
  • Mouse genes Atp12a
  • Rat genes Atp12a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp12a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008900	P-type potassium:proton transporter activity	ATP12A	IDA		Human	PMID:8853415
Molecular Function	GO:0008900	P-type potassium:proton transporter activity	Atp12a	IDA		Rat	PMID:16046397|RGD:2301240
Molecular Function	GO:0005391	P-type sodium:potassium-exchanging transporter activity	ATP12A	IDA		Human	PMID:9774385
Molecular Function	GO:0005515	protein binding	Atp12a	IPI	PR:P41731	Mouse	PMID:15647390
Molecular Function	GO:0005515	protein binding	Atp12a	IPI	UniProtKB:P07340	Rat	PMID:14749213|RGD:42722003
Molecular Function	GO:0005515	protein binding	Atp12a	IPI	UniProtKB:Q63377	Rat	PMID:9950762|RGD:42721995
Cellular Component	GO:0015629	actin cytoskeleton	ATP12A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016324	apical plasma membrane	ATP12A	IDA		Human	PMID:16914892
Cellular Component	GO:0016324	apical plasma membrane	Atp12a	IDA		Rat	PMID:11880279|RGD:2301242
Cellular Component	GO:0016324	apical plasma membrane	Atp12a	IDA		Rat	PMID:14749213|RGD:42722003
Cellular Component	GO:0016324	apical plasma membrane	Atp12a	IDA		Rat	PMID:15327400|RGD:2302991
Cellular Component	GO:0016324	apical plasma membrane	Atp12a	IDA		Rat	PMID:9950762|RGD:42721995
Cellular Component	GO:0016323	basolateral plasma membrane	Atp12a	IMP	MGI:MGI:2177160	Mouse	PMID:16525125
Cellular Component	GO:0005829	cytosol	ATP12A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ATP12A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Atp12a	IDA		Rat	PMID:9729517|RGD:13838663
Biological Process	GO:0055075	potassium ion homeostasis	Atp12a	IMP	MGI:MGI:1926943	Mouse	PMID:9449685
Biological Process	GO:0006885	regulation of pH	Atp12a	IMP	MGI:MGI:2177160	Mouse	PMID:16525125
Biological Process	GO:0010038	response to metal ion	Atp12a	IDA		Rat	PMID:16046397|RGD:2301240
Biological Process	GO:0014070	response to organic cyclic compound	Atp12a	IDA		Rat	PMID:16046397|RGD:2301240

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern