Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATF6B
  • Mouse genes Atf6b
  • Rat genes Atf6b
  • Zfish genes atf6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atf6b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ATF6B	IDA		Human	PMID:14973138
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ATF6B	IDA		Human	PMID:11256944
Molecular Function	GO:0005515	protein binding	ATF6B	IPI	UniProtKB:P27958:PRO_0000037575	Human	PMID:12445808
Molecular Function	GO:0005515	protein binding	ATF6B	IPI	UniProtKB:P17861	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	ATF6B	IPI	UniProtKB:P18850	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	Atf6b	IPI	UniProtKB:P20029	Mouse	MGI:MGI:3623653|PMID:16595634
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ATF6B	IDA		Human	PMID:11256944
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ATF6B	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ATF6B	IDA		Human	PMID:11256944
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ATF6B	IDA		Human	PMID:11256944
Cellular Component	GO:0005634	nucleus	ATF6B	IDA		Human	PMID:11256944
Cellular Component	GO:0032993	protein-DNA complex	ATF6B	IDA		Human	PMID:11256944
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ATF6B	IPI		Human	PMID:23661758
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ATF6B	IDA		Human	PMID:11256944
Biological Process	GO:1903892	negative regulation of ATF6-mediated unfolded protein response	ATF6B	IDA		Human	PMID:9837962
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ATF6B	IDA		Human	PMID:14973138
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	ATF6B	IDA		Human	PMID:11256944

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern