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Atf6b Gene Detail
Summary
  • Symbol
    Atf6b
  • Name
    activating transcription factor 6 beta
  • Synonyms
    ATF6beta, Crebl1, Creb-rp
  • Feature Type
    protein coding gene
  • IDs
    MGI:105121
    NCBI Gene: 12915
  • Gene Overview
    MyGene.info: ATF6B
Location & Maps
more
  • Sequence Map
    Chr17:34647146-34655074 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7929 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ATF6B, activating transcription factor 6 beta
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ATF6B, activating transcription factor 6 beta
    Orthology source: HomoloGene
  • Synonyms
    CREBL1, CREB-RP, G13
  • Links
    NCBI Gene ID: 1388
    neXtProt AC: NX_Q99941

  • Chr Location
    6p21.3; chr6:32115268-32128240 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased cellular sensitivity to thapsigargin and tunicamycin.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037081 VEGA Gene Model | MGI Sequence Detail 7929 C57BL/6J ±  kb
transcript OTTMUST00000095432 VEGA | MGI Sequence Detail 2315 Not Applicable  
polypeptide OTTMUSP00000053252 VEGA | MGI Sequence Detail 709 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000004403 cyclic AMP-dependent transcription factor ATF-6 beta
  • InterPro Domains
    IPR004827 Basic-leucine zipper domain
    IPR029809 cAMP-dependent transcription factor ATF-6 beta
Molecular
Reagents
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  • All nucleic 67
    Genomic 1
    cDNA 64
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-32162, MGI:2146775
References
more
  • Summaries
    All 41
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:29912 Min J, et al., A novel Creb family gene telomeric of HLA-DRA in the HLA complex. Genomics. 1995 Nov 20;30(2):149-56
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory