Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP6
  • Mouse genes Arhgap6
  • Rat genes Arhgap6
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	Arhgap6	IDA		Mouse	PMID:10699171
Cellular Component	GO:0015629	actin cytoskeleton	Arhgap6	IDA		Mouse	PMID:10699171
Cellular Component	GO:0005737	cytoplasm	ARHGAP6	IMP		Human	PMID:10699171
Cellular Component	GO:0005829	cytosol	ARHGAP6	IDA		Human	GO_REF:0000052
Biological Process	GO:0007015	actin filament organization	Arhgap6	IDA		Mouse	PMID:10699171
Biological Process	GO:0048041	focal adhesion assembly	Arhgap6	IDA		Mouse	PMID:10699171
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	ARHGAP6	IMP		Human	PMID:10699171
Biological Process	GO:0051497	negative regulation of stress fiber assembly	ARHGAP6	IMP		Human	PMID:10699171
Biological Process	GO:0043547	positive regulation of GTPase activity	Arhgap6	IDA		Mouse	MGI:MGI:2447568|PMID:10699171
Biological Process	GO:0043087	regulation of GTPase activity	Arhgap6	IDA		Mouse	PMID:10699171

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern