Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APOL1
  • Mouse genes Apol11a
  • Rat genes Apol11a
  • Zfish genes apol
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Apol11a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005254	chloride channel activity	APOL1	IDA		Human	PMID:16020735
Molecular Function	GO:0008289	lipid binding	APOL1	IDA		Human	PMID:16020735
Molecular Function	GO:0005515	protein binding	APOL1	IPI	UniProtKB:Q26807	Human	PMID:12621437
Molecular Function	GO:0005515	protein binding	APOL1	IPI	UniProtKB:Q8IXL6	Human	PMID:22582013
Molecular Function	GO:0005515	protein binding	APOL1	IPI	UniProtKB:Q9UJX2	Human	PMID:25416956
Cellular Component	GO:0072562	blood microparticle	APOL1	HDA		Human	PMID:22516433
Cellular Component	GO:0005615	extracellular space	APOL1	IDA		Human	PMID:17192540
Cellular Component	GO:0034364	high-density lipoprotein particle	APOL1	IDA		Human	PMID:9325276
Cellular Component	GO:0034361	very-low-density lipoprotein particle	APOL1	IDA		Human	PMID:17154273
Biological Process	GO:1902476	chloride transmembrane transport	APOL1	IDA		Human	PMID:16020735
Biological Process	GO:0051838	cytolysis by host of symbiont cells	APOL1	IDA		Human	PMID:12621437
Biological Process	GO:0051838	cytolysis by host of symbiont cells	APOL1	IDA		Human	PMID:17192540
Biological Process	GO:0045087	innate immune response	APOL1	IDA		Human	PMID:17192540

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern