Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AP3B1
  • Mouse genes Ap3b1
  • Rat genes Ap3b1
  • Zfish genes ap3b1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ap3b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030742	GTP-dependent protein binding	AP3B1	IPI	UniProtKB:P57729	Human	PMID:22511774
Molecular Function	GO:0030742	GTP-dependent protein binding	AP3B1	IPI	UniProtKB:Q13637	Human	PMID:22511774
Molecular Function	GO:0005515	protein binding	AP3B1	IPI	UniProtKB:Q5S007	Human	PMID:24725412
Molecular Function	GO:0005515	protein binding	AP3B1	IPI	UniProtKB:Q5S007	Human	PMID:27424887
Molecular Function	GO:0005515	protein binding	AP3B1	IPI	UniProtKB:A0A0S2Z5Q7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AP3B1	IPI	UniProtKB:O14645	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AP3B1	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AP3B1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AP3B1	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AP3B1	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0019903	protein phosphatase binding	AP3B1	IPI	UniProtKB:Q92729	Human	PMID:17622474
Cellular Component	GO:0005765	lysosomal membrane	AP3B1	HDA		Human	PMID:17897319
Cellular Component	GO:0016020	membrane	AP3B1	HDA		Human	PMID:19946888
Biological Process	GO:0008089	anterograde axonal transport	Ap3b1	IMP		Mouse	MGI:MGI:5437407|PMID:21998198
Biological Process	GO:0048490	anterograde synaptic vesicle transport	Ap3b1	IMP		Mouse	MGI:MGI:5437407|PMID:21998198
Biological Process	GO:0019882	antigen processing and presentation	Ap3b1	IMP	MGI:MGI:1856989	Mouse	PMID:14557411
Biological Process	GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	Ap3b1	IMP	MGI:MGI:1856989	Mouse	PMID:14557411
Biological Process	GO:0007596	blood coagulation	Ap3b1	IMP	MGI:MGI:1856989	Mouse	PMID:6696991
Biological Process	GO:0000902	cell morphogenesis	Ap3b1	IGI	MGI:MGI:2177763	Mouse	PMID:12777251
Biological Process	GO:0090152	establishment of protein localization to mitochondrial membrane involved in mitochondrial fission	Ap3b1	IMP		Mouse	PMID:11058094
Biological Process	GO:0030851	granulocyte differentiation	Ap3b1	IMP		Mouse	PMID:23748140
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Ap3b1	IMP		Mouse	PMID:23748140
Biological Process	GO:0048872	homeostasis of number of cells	Ap3b1	IMP		Mouse	PMID:23748140
Biological Process	GO:0006954	inflammatory response	Ap3b1	IGI	MGI:MGI:1333879	Mouse	PMID:12777251
Biological Process	GO:0032607	interferon-alpha production	Ap3b1	IMP		Mouse	PMID:20847273
Biological Process	GO:0006886	intracellular protein transport	Ap3b1	IMP		Mouse	PMID:20847273
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Ap3b1	IMP		Mouse	PMID:30786955
Biological Process	GO:0030324	lung development	Ap3b1	IGI	MGI:MGI:2177763	Mouse	PMID:12777251
Biological Process	GO:0060425	lung morphogenesis	Ap3b1	IGI	MGI:MGI:2177763	Mouse	PMID:12777251
Biological Process	GO:0007040	lysosome organization	Ap3b1	IMP		Mouse	PMID:9931340
Biological Process	GO:0007040	lysosome organization	Ap3b1	IMP		Mouse	PMID:30786955
Biological Process	GO:0032438	melanosome organization	AP3B1	IMP		Human	PMID:11452004
Biological Process	GO:0032438	melanosome organization	AP3B1	IMP		Human	PMID:19841138
Biological Process	GO:0032438	melanosome organization	Ap3b1	IMP		Mouse	PMID:9931340
Biological Process	GO:0061024	membrane organization	Ap3b1	IMP		Mouse	PMID:11058094
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	Ap3b1	IMP		Mouse	PMID:31272455
Biological Process	GO:0043473	pigmentation	Ap3b1	IMP		Mouse	PMID:9931340
Biological Process	GO:0060155	platelet dense granule organization	Ap3b1	IMP		Mouse	PMID:9931340
Biological Process	GO:0051138	positive regulation of NK T cell differentiation	Ap3b1	IMP	MGI:MGI:1856989	Mouse	PMID:14557411
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ap3b1	IMP		Mouse	PMID:20847273
Biological Process	GO:0034394	protein localization to cell surface	Ap3b1	IMP		Mouse	PMID:11058094
Biological Process	GO:0036211	protein modification process	Ap3b1	IMP		Mouse	PMID:20847273
Biological Process	GO:0006622	protein targeting to lysosome	Ap3b1	IMP	MGI:MGI:1856989	Mouse	PMID:14557411
Biological Process	GO:0050790	regulation of catalytic activity	Ap3b1	IMP		Mouse	PMID:31272455
Biological Process	GO:0003016	respiratory system process	Ap3b1	IGI	MGI:MGI:1333879	Mouse	PMID:12777251
Biological Process	GO:0007338	single fertilization	Ap3b1	IMP		Mouse	PMID:30786955
Biological Process	GO:0098773	skin epidermis development	Ap3b1	IMP		Mouse	PMID:11058094
Biological Process	GO:0007283	spermatogenesis	Ap3b1	IMP		Mouse	PMID:30786955
Biological Process	GO:0002224	toll-like receptor signaling pathway	Ap3b1	IMP		Mouse	PMID:20847273
Biological Process	GO:0032606	type I interferon production	Ap3b1	IMP		Mouse	PMID:20847273

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern