Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ano1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ANO1
- Mouse genes Ano1
- Rat genes Ano1
- Zfish genes ano1a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ano1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005227	calcium activated cation channel activity	ANO1	IDA		Human	PMID:22946059
Molecular Function	GO:0005254	chloride channel activity	ANO1	IMP		Human	PMID:24885604
Molecular Function	GO:0005254	chloride channel activity	ANO1	IMP		Human	PMID:28963502
Molecular Function	GO:0005254	chloride channel activity	ANO1	IDA		Human	PMID:32487539
Molecular Function	GO:0005254	chloride channel activity	Ano1	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Molecular Function	GO:0005254	chloride channel activity	Ano1	IDA		Mouse	MGI:MGI:6460582\|PMID:25779870
Molecular Function	GO:0005254	chloride channel activity	Ano1	IDA		Mouse	MGI:MGI:6315451\|PMID:31147466
Molecular Function	GO:0005254	chloride channel activity	Ano1	IMP		Mouse	MGI:MGI:6109368\|PMID:28963502
Molecular Function	GO:0042802	identical protein binding	ANO1	IPI	UniProtKB:Q5XXA6	Human	PMID:28559167
Molecular Function	GO:0042802	identical protein binding	Ano1	IPI	UniProtKB:Q8BHY3	Mouse	MGI:MGI:6478062\|PMID:29236684
Molecular Function	GO:0042802	identical protein binding	Ano1	IPI	UniProtKB:Q8BHY3	Mouse	MGI:MGI:6478063\|PMID:29236691
Molecular Function	GO:0042802	identical protein binding	Ano1	IPI	PR:Q8BHY3	Mouse	PMID:23576756
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	ANO1	IDA		Human	PMID:21984732
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	ANO1	IMP		Human	PMID:22178883
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	ANO1	IMP		Human	PMID:22946059
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IDA		Mouse	MGI:MGI:3815244\|PMID:18724360
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IDA		Mouse	MGI:MGI:5461590\|PMID:22634729
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IDA		Mouse	MGI:MGI:5448512\|PMID:22075693
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IDA		Mouse	MGI:MGI:6316357\|PMID:28561733
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IDA		Mouse	PMID:23532839
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IDA		Mouse	PMID:20056604
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IDA		Mouse	PMID:23576756
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IMP		Rat	PMID:20421283\|RGD:9684846
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IDA		Rat	PMID:24081981\|RGD:9684847
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano1	IMP		Rat	PMID:25201006\|RGD:10047211
Molecular Function	GO:0015111	iodide transmembrane transporter activity	ANO1	IMP		Human	PMID:25201006
Molecular Function	GO:0015111	iodide transmembrane transporter activity	Ano1	IMP		Rat	PMID:25201006\|RGD:10047211
Molecular Function	GO:0005515	protein binding	ANO1	IPI	UniProtKB:P13569	Human	PMID:22178883
Molecular Function	GO:0005515	protein binding	Ano1	IPI	PR:Q8CFW1	Mouse	PMID:23576756
Molecular Function	GO:0042803	protein homodimerization activity	Ano1	IDA		Mouse	MGI:MGI:6316357\|PMID:28561733
Molecular Function	GO:0005102	signaling receptor binding	Ano1	IPI	RGD:2933	Rat	PMID:23982204\|RGD:14696826
Molecular Function	GO:0005247	voltage-gated chloride channel activity	Ano1	IDA		Mouse	MGI:MGI:5461590\|PMID:22634729
Cellular Component	GO:0016324	apical plasma membrane	ANO1	IDA		Human	PMID:25201006
Cellular Component	GO:0016324	apical plasma membrane	ANO1	IDA		Human	PMID:31732694
Cellular Component	GO:0016324	apical plasma membrane	ANO1	IDA		Human	PMID:32487539
Cellular Component	GO:0016324	apical plasma membrane	Ano1	IDA		Mouse	PMID:21516098
Cellular Component	GO:0009897	external side of plasma membrane	Ano1	IDA		Mouse	PMID:23576756
Cellular Component	GO:0070062	extracellular exosome	ANO1	HDA		Human	PMID:19199708
Cellular Component	GO:0098978	glutamatergic synapse	Ano1	IDA		Mouse	PMID:23840801
Cellular Component	GO:0045121	membrane raft	Ano1	IDA		Rat	PMID:23982204\|RGD:14696826
Cellular Component	GO:0005654	nucleoplasm	ANO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ANO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ANO1	IDA		Human	PMID:21984732
Cellular Component	GO:0005886	plasma membrane	ANO1	IDA		Human	PMID:22178883
Cellular Component	GO:0005886	plasma membrane	ANO1	IDA		Human	PMID:22946059
Cellular Component	GO:0005886	plasma membrane	ANO1	IDA		Human	PMID:28559167
Cellular Component	GO:0005886	plasma membrane	Ano1	IDA		Mouse	MGI:MGI:6316357\|PMID:28561733
Cellular Component	GO:0005886	plasma membrane	Ano1	IDA		Mouse	MGI:MGI:3805598\|PMID:18585372
Cellular Component	GO:0005886	plasma membrane	Ano1	IDA		Mouse	MGI:MGI:5448512\|PMID:22075693
Cellular Component	GO:0005886	plasma membrane	Ano1	IDA		Mouse	PMID:20056604
Cellular Component	GO:0005886	plasma membrane	Ano1	IDA		Rat	PMID:24081981\|RGD:9684847
Cellular Component	GO:0042734	presynaptic membrane	Ano1	IDA		Mouse	PMID:23840801
Biological Process	GO:0034605	cellular response to heat	Ano1	IDA		Mouse	MGI:MGI:5461590\|PMID:22634729
Biological Process	GO:1901653	cellular response to peptide	Ano1	IMP		Rat	PMID:20335661\|RGD:14696827
Biological Process	GO:1902476	chloride transmembrane transport	ANO1	IMP		Human	PMID:24885604
Biological Process	GO:1902476	chloride transmembrane transport	ANO1	IDA		Human	PMID:32487539
Biological Process	GO:1902476	chloride transmembrane transport	Ano1	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Biological Process	GO:1902476	chloride transmembrane transport	Ano1	IDA		Mouse	MGI:MGI:5461590\|PMID:22634729
Biological Process	GO:1902476	chloride transmembrane transport	Ano1	IDA		Mouse	MGI:MGI:6316357\|PMID:28561733
Biological Process	GO:1902476	chloride transmembrane transport	Ano1	IMP		Rat	PMID:23982204\|RGD:14696826
Biological Process	GO:0006821	chloride transport	ANO1	IMP		Human	PMID:22946059
Biological Process	GO:0006821	chloride transport	ANO1	IMP		Human	PMID:28963502
Biological Process	GO:0006821	chloride transport	Ano1	IMP		Mouse	MGI:MGI:6109368\|PMID:28963502
Biological Process	GO:0006821	chloride transport	Ano1	IDA		Mouse	MGI:MGI:3815244\|PMID:18724360
Biological Process	GO:0006821	chloride transport	Ano1	IDA		Mouse	PMID:20056604
Biological Process	GO:0006821	chloride transport	Ano1	IDA		Mouse	PMID:23532839
Biological Process	GO:0006821	chloride transport	Ano1	IMP		Rat	PMID:25201006\|RGD:10047211
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	Ano1	IMP		Mouse	MGI:MGI:5461590\|PMID:22634729
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	Ano1	IGI	UniProtKB:Q704Y3	Mouse	MGI:MGI:5461590\|PMID:22634729
Biological Process	GO:0051649	establishment of localization in cell	Ano1	IDA		Mouse	PMID:23532839
Biological Process	GO:0106091	glial cell projection elongation	Ano1	IMP		Mouse	MGI:MGI:6315451\|PMID:31147466
Biological Process	GO:0015705	iodide transport	ANO1	IMP		Human	PMID:25201006
Biological Process	GO:0015705	iodide transport	Ano1	IMP		Rat	PMID:25201006\|RGD:10047211
Biological Process	GO:0006812	monoatomic cation transport	ANO1	IDA		Human	PMID:22946059
Biological Process	GO:0070254	mucus secretion	ANO1	IMP		Human	PMID:33026825
Biological Process	GO:0070254	mucus secretion	Ano1	IMP		Mouse	MGI:MGI:6390287\|PMID:30586313
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Ano1	IDA		Mouse	MGI:MGI:5461590\|PMID:22634729
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ANO1	IGI	UniProtKB:P13569	Human	PMID:24885604
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ANO1	IMP		Human	PMID:24885604
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Ano1	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Biological Process	GO:0072657	protein localization to membrane	ANO1	IMP		Human	PMID:28963502
Biological Process	GO:0042391	regulation of membrane potential	Ano1	IMP		Mouse	PMID:23133519
Biological Process	GO:0042391	regulation of membrane potential	Ano1	IGI	MGI:MGI:1918361	Mouse	PMID:23133519
Biological Process	GO:0060438	trachea development	Ano1	IMP		Mouse	MGI:MGI:3805598\|PMID:18585372

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.