Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANGPTL1
  • Mouse genes Angptl1
  • Rat genes Angptl1
  • Zfish genes angptl1a,angptl1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Angptl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005102	signaling receptor binding	Angptl1	IPI	PR:Q02858	Mouse	PMID:10051567
Cellular Component	GO:0070062	extracellular exosome	ANGPTL1	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	ANGPTL1	IDA		Human	PMID:10025962
Biological Process	GO:0001525	angiogenesis	angptl1a	IGI	ZFIN:ZDB-MRPHLNO-051019-1,ZFIN:ZDB-MRPHLNO-051020-1	Zfish	PMID:16174743
Biological Process	GO:0060216	definitive hemopoiesis	angptl1a	IGI	ZFIN:ZDB-GENE-050624-1	Zfish	PMID:25714926
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	angptl1a	IGI	ZFIN:ZDB-GENE-050624-1	Zfish	PMID:25714926
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	angptl1a	IGI	ZFIN:ZDB-GENE-040426-780,ZFIN:ZDB-GENE-050624-1	Zfish	PMID:25714926
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	angptl1a	IGI	ZFIN:ZDB-GENE-050624-1	Zfish	PMID:25714926
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Angptl1	IPI	PR:Q02858	Mouse	PMID:10051567

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern