Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AMOTL1
  • Mouse genes Amotl1
  • Rat genes Amotl1
  • Zfish genes amotl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Amotl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	AMOTL1	IDA		Human	PMID:16019084
Molecular Function	GO:0005515	protein binding	AMOTL1	IPI	UniProtKB:P46937	Human	PMID:21187284
Molecular Function	GO:0005515	protein binding	Amotl1	IPI	PR:Q8JZS0	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Amotl1	IPI	PR:Q8VBX6	Mouse	PMID:17397395
Molecular Function	GO:0005515	protein binding	Amotl1	IPI	PR:Q8VBX6	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Amotl1	IPI	PR:Q63ZW7	Mouse	PMID:17397395
Molecular Function	GO:0005515	protein binding	Amotl1	IPI	PR:Q66T02	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Amotl1	IPI	PR:Q9JLB2	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Amotl1	IPI	PR:Q8VHG2	Mouse	PMID:19590046
Cellular Component	GO:0016324	apical plasma membrane	Amotl1	IDA		Mouse	PMID:17397395
Cellular Component	GO:0005923	bicellular tight junction	AMOTL1	IDA		Human	PMID:16019084
Cellular Component	GO:0005923	bicellular tight junction	Amotl1	IDA		Mouse	PMID:19590046
Cellular Component	GO:0005923	bicellular tight junction	Amotl1	IDA		Mouse	PMID:11733531
Cellular Component	GO:0005923	bicellular tight junction	Amotl1	IDA		Mouse	PMID:17397395
Cellular Component	GO:0031410	cytoplasmic vesicle	Amotl1	IDA		Mouse	PMID:17397395
Cellular Component	GO:0030027	lamellipodium	Amotl1	IDA		Mouse	PMID:19590046
Biological Process	GO:0001568	blood vessel development	amotl1	IMP	ZFIN:ZDB-MRPHLNO-091014-1	Zfish	PMID:19590046
Biological Process	GO:0043534	blood vessel endothelial cell migration	Amotl1	IMP		Mouse	PMID:19590046
Biological Process	GO:0098609	cell-cell adhesion	amotl1	IMP	ZFIN:ZDB-MRPHLNO-091014-1	Zfish	PMID:19590046
Biological Process	GO:0003365	establishment of cell polarity involved in ameboidal cell migration	Amotl1	IMP		Mouse	PMID:19590046
Biological Process	GO:0090162	establishment of epithelial cell polarity	Amotl1	IMP		Mouse	PMID:19590046
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	Amotl1	IMP		Mouse	PMID:19590046

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern