Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AMN
  • Mouse genes Amn
  • Rat genes Amn
  • Zfish genes amn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Amn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0038024	cargo receptor activity	AMN	IDA		Human	PMID:14576052
Molecular Function	GO:0005515	protein binding	AMN	IPI	UniProtKB:O60494	Human	PMID:30523278
Molecular Function	GO:0005102	signaling receptor binding	AMN	IPI	UniProtKB:O60494	Human	PMID:14576052
Cellular Component	GO:0045177	apical part of cell	Amn	IDA		Mouse	PMID:15342463
Cellular Component	GO:0016324	apical plasma membrane	AMN	IDA		Human	PMID:14576052
Cellular Component	GO:0031526	brush border membrane	Amn	IDA		Rat	PMID:17990981|RGD:2317831
Cellular Component	GO:0030139	endocytic vesicle	AMN	IDA		Human	PMID:14576052
Cellular Component	GO:0030139	endocytic vesicle	Amn	IDA		Rat	PMID:24122887|RGD:11250404
Cellular Component	GO:0070062	extracellular exosome	AMN	HDA		Human	PMID:19056867
Cellular Component	GO:0005615	extracellular space	AMN	IDA		Human	PMID:14576052
Cellular Component	GO:0016020	membrane	AMN	IDA		Human	PMID:14576052
Cellular Component	GO:0031528	microvillus membrane	AMN	IDA		Human	PMID:14576052
Cellular Component	GO:0032991	protein-containing complex	Amn	IDA		Rat	PMID:17990981|RGD:2317831
Cellular Component	GO:0043235	receptor complex	AMN	IPI		Human	PMID:30523278
Biological Process	GO:0009235	cobalamin metabolic process	AMN	IDA		Human	PMID:14576052
Biological Process	GO:0015889	cobalamin transport	AMN	IDA		Human	PMID:14576052
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	AMN	IDA		Human	PMID:14576052
Biological Process	GO:0008104	protein localization	Amn	IMP	MGI:MGI:2135304	Mouse	PMID:15342463
Biological Process	GO:0008104	protein localization	Amn	IMP	MGI:MGI:2135454	Mouse	PMID:15342463
Biological Process	GO:0006898	receptor-mediated endocytosis	AMN	IDA		Human	PMID:14576052
Biological Process	GO:0006898	receptor-mediated endocytosis	AMN	IMP		Human	PMID:20088845
Biological Process	GO:0097017	renal protein absorption	Amn	IMP	MGI:MGI:2135304	Mouse	PMID:15342463
Biological Process	GO:0097017	renal protein absorption	Amn	IMP	MGI:MGI:2135454	Mouse	PMID:15342463

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern