Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALPK1
  • Mouse genes Alpk1
  • Rat genes Alpk1
  • Zfish genes alpk1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alpk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048029	monosaccharide binding	ALPK1	IPI	CHEBI:59967	Human	PMID:30111836
Molecular Function	GO:0005515	protein binding	ALPK1	IPI	UniProtKB:Q96CG3	Human	PMID:30111836
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ALPK1	EXP		Human	PMID:30111836
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ALPK1	IDA		Human	PMID:30111836
Cellular Component	GO:0005813	centrosome	ALPK1	IDA		Human	PMID:30967659
Cellular Component	GO:0005929	cilium	ALPK1	IDA		Human	PMID:30967659
Cellular Component	GO:0005829	cytosol	ALPK1	IDA		Human	PMID:30111836
Cellular Component	GO:0032391	photoreceptor connecting cilium	Alpk1	IDA		Mouse	MGI:MGI:6717246|PMID:30967659
Cellular Component	GO:0000922	spindle pole	ALPK1	IDA		Human	PMID:30967659
Biological Process	GO:0060271	cilium assembly	ALPK1	IMP		Human	PMID:30967659
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	ALPK1	IDA		Human	PMID:28222186
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	ALPK1	IDA		Human	PMID:28877472
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	ALPK1	IDA		Human	PMID:30111836
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	Alpk1	IMP		Mouse	MGI:MGI:6196443|PMID:30111836
Biological Process	GO:0045087	innate immune response	ALPK1	IDA		Human	PMID:28222186
Biological Process	GO:0045087	innate immune response	ALPK1	IDA		Human	PMID:28877472
Biological Process	GO:0045087	innate immune response	ALPK1	IDA		Human	PMID:30111836
Biological Process	GO:0045087	innate immune response	Alpk1	IMP		Mouse	MGI:MGI:6196443|PMID:30111836
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ALPK1	IDA		Human	PMID:28222186
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ALPK1	IDA		Human	PMID:28877472
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ALPK1	IDA		Human	PMID:30111836
Biological Process	GO:0009617	response to bacterium	Alpk1	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern