Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH7A1
  • Mouse genes Aldh7a1
  • Rat genes Aldh7a1
  • Zfish genes aldh7a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh7a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH7A1	IDA		Human	PMID:20207735
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH7A1	IDA		Human	PMID:21338592
Molecular Function	GO:0043741	alpha-aminoadipate acetyltransferase activity	aldh7a1	IMP	ZFIN:ZDB-GENO-190411-15	Zfish	PMID:29053735
Molecular Function	GO:0008802	betaine-aldehyde dehydrogenase activity	ALDH7A1	IDA		Human	PMID:20207735
Molecular Function	GO:0042802	identical protein binding	ALDH7A1	IDA		Human	PMID:20207735
Molecular Function	GO:0005515	protein binding	ALDH7A1	IPI	UniProtKB:Q12929	Human	PMID:21988832
Cellular Component	GO:0005829	cytosol	ALDH7A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	ALDH7A1	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	ALDH7A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Aldh7a1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Aldh7a1	HDA		Mouse	PMID:18614015
Biological Process	GO:0043010	camera-type eye development	aldh7a1	IGI	ZFIN:ZDB-GENE-010717-1,ZFIN:ZDB-MRPHLNO-141014-5	Zfish	PMID:25004007
Biological Process	GO:0043010	camera-type eye development	aldh7a1	IMP	ZFIN:ZDB-MRPHLNO-141014-5	Zfish	PMID:25004007
Biological Process	GO:0043010	camera-type eye development	aldh7a1	IMP	ZFIN:ZDB-MRPHLNO-141014-6	Zfish	PMID:25004007
Biological Process	GO:0043010	camera-type eye development	aldh7a1	IMP	ZFIN:ZDB-MRPHLNO-141014-5,ZFIN:ZDB-MRPHLNO-141014-6	Zfish	PMID:25004007
Biological Process	GO:0051216	cartilage development	aldh7a1	IMP	ZFIN:ZDB-MRPHLNO-141014-5	Zfish	PMID:25004007
Biological Process	GO:0033339	pectoral fin development	aldh7a1	IMP	ZFIN:ZDB-MRPHLNO-141014-5	Zfish	PMID:25004007

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern