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Aldh7a1
Gene Detail
Symbol

Name
ID
Aldh7a1
aldehyde dehydrogenase family 7, member A1
MGI:108186
Synonyms
Atq1, D18Wsu181e
Feature Type
protein coding gene
Genetic Map
Chromosome 18
30.55 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr18:56509687-56572951 bp, - strand
From VEGA annotation of GRCm38

  63265 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:913  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: NAD-dependent aldehyde dehydrogenase
Gene Tree: Aldh7a1

Human
homologs
Human Homolog ALDH7A1, aldehyde dehydrogenase 7 family, member A1
NCBI Gene ID 501
neXtProt AC  NX_P49419
Human Synonyms  ATQ1, EPD, PDE
Human Chr (Location)  5q31; chr5:126541841-126595390 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALDH7A1
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(15) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display a normal phenotype.
 
Interactions
Aldh7a1 interacts with 246 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (265)    Tissues (155)    Images (45)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 259
RT-PCR 6
cDNA source data(204)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(208) cDNA(205) Primer pair(3)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000035214 (Evidence)
Ensembl Gene ModelENSMUSG00000053644 (Evidence)
Entrez Gene110695 (Evidence)
UniGene30250
DFCITC1572084, TC1777657, TC1707961, TC1583648
NIA Mouse Gene IndexU058287
EC1.2.1.8, 1.2.1.31, 1.2.1.3
Consensus CDS ProjectCCDS29258.2, CCDS50291.1
International Mouse Knockout Project StatusAldh7a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035214 VEGA Gene Model | MGI Sequence Detail 63265 C57BL/6J ±  kb
transcript OTTMUST00000089709 VEGA | MGI Sequence Detail 1914 Not Applicable 
polypeptide OTTMUSP00000049051 VEGA | MGI Sequence Detail 539 Not Applicable 

For the selected sequences
All sequences(70) RefSeq(5) UniProt(9)
Polymorphisms
All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(781 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016163 Aldehyde dehydrogenase, C-terminal
InterPro IPR015590 Aldehyde dehydrogenase domain
InterPro IPR016162 Aldehyde dehydrogenase, N-terminal
InterPro IPR016161 Aldehyde/histidinol dehydrogenase
Protein Ontology PR:000003931 alpha-aminoadipic semialdehyde dehydrogenase
References
(Earliest) J:4717 Gill RK, et al., Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2984-8
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(45)
Other
accession IDs
MGD-MRK-36424, MGD-MRK-37225, MGI:107847

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory