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Aldh7a1 Gene Detail
Summary
  • Symbol
    Aldh7a1
  • Name
    aldehyde dehydrogenase family 7, member A1
  • Synonyms
    Atq1, D18Wsu181e
  • Feature Type
    protein coding gene
  • IDs
    MGI:108186
    NCBI Gene: 110695
  • Gene Overview
    MyGene.info: ALDH7A1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:56524722-56572939 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 30.55 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    515 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108186
protein coding gene Chr18:56509687-56572951 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024441
protein coding gene Chr18:55870564-55943650 (-)
A/J MGP_AJ_G0024407
protein coding gene Chr18:53666050-53733632 (-)
AKR/J MGP_AKRJ_G0024377
protein coding gene Chr18:55128538-55201784 (-)
BALB/cJ MGP_BALBcJ_G0024407
protein coding gene Chr18:53850842-53915828 (-)
C3H/HeJ MGP_C3HHeJ_G0024174
protein coding gene Chr18:55357752-55423721 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024853
protein coding gene Chr18:57645397-57711599 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022285
protein coding gene Chr18:53303444-53370561 (-)
CAST/EiJ MGP_CASTEiJ_G0023648
protein coding gene Chr18:55369218-55443956 (-)
CBA/J MGP_CBAJ_G0024144
protein coding gene Chr18:59450021-59519127 (-)
DBA/2J MGP_DBA2J_G0024274
protein coding gene Chr18:53366422-53430298 (-)
FVB/NJ MGP_FVBNJ_G0024241
protein coding gene Chr18:52752510-52817762 (-)
LP/J MGP_LPJ_G0024359
protein coding gene Chr18:55841490-55905698 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024271
protein coding gene Chr18:61127728-61198595 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024900
protein coding gene Chr18:55252984-55320167 (-)
PWK/PhJ MGP_PWKPhJ_G0023392
protein coding gene Chr18:53377269-53445251 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023198
protein coding gene Chr18:55337558-55400511 (-)
WSB/EiJ MGP_WSBEiJ_G0023711
protein coding gene Chr18:55175333-55241911 (-)



Homology
more
  • Human Ortholog
    ALDH7A1, aldehyde dehydrogenase 7 family member A1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ALDH7A1, aldehyde dehydrogenase 7 family member A1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ATQ1, EPD, PDE
  • Links
    NCBI Gene ID: 501
    neXtProt AC: NX_P49419
    UniProt: P49419

  • Chr Location
    5q23.2; chr5:126541841-126595390 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 110695 NCBI Gene Model | MGI Sequence Detail 48218 C57BL/6J ±  kb
transcript NM_001127338 RefSeq | MGI Sequence Detail 3105 C57BL/6  
polypeptide Q9DBF1 UniProt | EBI | MGI Sequence Detail 539 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 209
    cDNA 206
    Primer pair 3

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-36424, MGD-MRK-37225, MGI:107847
References
more
  • Summaries
    All 44
    Developmental Gene Expression 6
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:4717 Gill RK, et al., Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2984-8
  • Latest
    J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory