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Aldh7a1 Gene Detail
Summary
  • Symbol
    Aldh7a1
  • Name
    aldehyde dehydrogenase family 7, member A1
  • Synonyms
    Atq1, D18Wsu181e
  • Feature Type
    protein coding gene
  • IDs
    MGI:108186
    NCBI Gene: 110695
  • Gene Overview
    MyGene.info: ALDH7A1
Location & Maps
more
  • Sequence Map
    Chr18:56509687-56572951 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      63265 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 30.55 cM
  • Mapping Data
    7 experiments
Homology
more
  • Human Ortholog
    ALDH7A1, aldehyde dehydrogenase 7 family member A1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ALDH7A1, aldehyde dehydrogenase 7 family member A1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ATQ1, EPD, PDE
  • Links
    NCBI Gene ID: 501
    neXtProt AC: NX_P49419

  • Chr Location
    5q23.2; chr5:126541841-126595390 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ALDH7A1 associations

Human Disease Mouse Models
       Epilepsy, Pyridoxine-Dependent; EPD   OMIM: 266100
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
  • All Mutations and Alleles
    17
  • Gene trapped
    15
  • Targeted
    2
  • Incidental Mutations
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035214 VEGA Gene Model | MGI Sequence Detail 63265 C57BL/6J ±  kb
transcript OTTMUST00000089709 VEGA | MGI Sequence Detail 1914 Not Applicable  
polypeptide OTTMUSP00000049051 VEGA | MGI Sequence Detail 539 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    768 from dbSNP Build 142
  • PCR
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 208
    cDNA 205
    Primer pair 3

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-36424, MGD-MRK-37225, MGI:107847
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:4717 Gill RK, et al., Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2984-8
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory