Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALCAM
  • Mouse genes Alcam
  • Rat genes Alcam
  • Zfish genes alcama,alcamb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alcam

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	ALCAM	IPI	UniProtKB:Q13740	Human	PMID:26146185
Molecular Function	GO:0042802	identical protein binding	alcamb	IDA		Zfish	PMID:18296487
Molecular Function	GO:0042802	identical protein binding	alcama	IDA		Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	ALCAM	IPI	UniProtKB:P09382	Human	PMID:24945728
Molecular Function	GO:0005515	protein binding	ALCAM	IPI	UniProtKB:P17931	Human	PMID:24945728
Molecular Function	GO:0005515	protein binding	ALCAM	IPI	UniProtKB:P30203	Human	PMID:24945728
Molecular Function	GO:0005515	protein binding	ALCAM	IPI	UniProtKB:P30203	Human	PMID:26146185
Molecular Function	GO:0005515	protein binding	Alcam	IPI	PR:Q61003	Mouse	PMID:9209500
Cellular Component	GO:0030424	axon	Alcam	IDA		Mouse	PMID:16267219
Cellular Component	GO:0030424	axon	alcamb	IDA		Zfish	PMID:19107846
Cellular Component	GO:0030424	axon	alcama	IDA		Zfish	PMID:19107846
Cellular Component	GO:0009897	external side of plasma membrane	Alcam	IDA		Mouse	PMID:9209500
Cellular Component	GO:0070062	extracellular exosome	ALCAM	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ALCAM	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	ALCAM	HDA		Human	PMID:21423176
Cellular Component	GO:0001772	immunological synapse	ALCAM	IDA		Human	PMID:15294938
Cellular Component	GO:0043025	neuronal cell body	Alcam	IDA		Mouse	PMID:16267219
Cellular Component	GO:0005886	plasma membrane	ALCAM	IDA		Human	PMID:15294938
Biological Process	GO:0007411	axon guidance	Alcam	IMP	MGI:MGI:3056579	Mouse	PMID:15345243
Biological Process	GO:0007409	axonogenesis	alcama	IMP	ZFIN:ZDB-MRPHLNO-090917-5	Zfish	PMID:19107846
Biological Process	GO:0060385	axonogenesis involved in innervation	alcamb	IMP	ZFIN:ZDB-MRPHLNO-090917-6	Zfish	PMID:19107846
Biological Process	GO:0060536	cartilage morphogenesis	alcama	IMP		Zfish	PMID:21073867|ZFIN:ZDB-PUB-101122-3
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	alcama	IMP	ZFIN:ZDB-MRPHLNO-110125-5	Zfish	PMID:21073867
Biological Process	GO:0021885	forebrain cell migration	alcamb	IMP	ZFIN:ZDB-MRPHLNO-090917-6	Zfish	PMID:20005219
Biological Process	GO:0001947	heart looping	alcama	IMP	ZFIN:ZDB-MRPHLNO-110125-4	Zfish	PMID:23533583
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	ALCAM	IMP		Human	PMID:16352806
Biological Process	GO:0008045	motor neuron axon guidance	Alcam	IMP	MGI:MGI:3056579	Mouse	PMID:15345243
Biological Process	GO:0014033	neural crest cell differentiation	alcama	IMP		Zfish	PMID:21073867|ZFIN:ZDB-PUB-101122-3
Biological Process	GO:0014033	neural crest cell differentiation	alcama	IMP	ZFIN:ZDB-MRPHLNO-110125-5	Zfish	PMID:21073867
Biological Process	GO:0030182	neuron differentiation	alcama	IMP	ZFIN:ZDB-MRPHLNO-090917-5	Zfish	PMID:19107846
Biological Process	GO:0010770	positive regulation of cell morphogenesis involved in differentiation	alcama	IMP		Zfish	PMID:21073867|ZFIN:ZDB-PUB-101122-3
Biological Process	GO:0010628	positive regulation of gene expression	alcama	IMP		Zfish	PMID:21073867|ZFIN:ZDB-PUB-101122-3
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	alcama	IMP	ZFIN:ZDB-MRPHLNO-090917-7	Zfish	PMID:19107846
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	alcama	IMP	ZFIN:ZDB-MRPHLNO-090917-5	Zfish	PMID:19107846
Biological Process	GO:0031290	retinal ganglion cell axon guidance	alcamb	IMP	ZFIN:ZDB-MRPHLNO-090917-6	Zfish	PMID:19107846

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern