Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AK4
  • Mouse genes Ak4
  • Rat genes Ak4
  • Zfish genes ak4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ak4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004017	adenylate kinase activity	AK4	IDA		Human	PMID:19766732
Molecular Function	GO:0004550	nucleoside diphosphate kinase activity	AK4	IDA		Human	PMID:23416111
Molecular Function	GO:0046899	nucleoside triphosphate adenylate kinase activity	AK4	IDA		Human	PMID:19766732
Molecular Function	GO:0005515	protein binding	AK4	IPI	UniProtKB:P05141	Human	PMID:19130895
Cellular Component	GO:0005759	mitochondrial matrix	Ak4	IDA		Mouse	MGI:MGI:2149139|PMID:11485571
Cellular Component	GO:0005739	mitochondrion	AK4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	AK4	IDA		Human	PMID:19766732
Cellular Component	GO:0005739	mitochondrion	AK4	IDA		Human	PMID:26980435
Cellular Component	GO:0005739	mitochondrion	Ak4	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ak4	HDA		Mouse	PMID:18614015
Biological Process	GO:0046033	AMP metabolic process	AK4	IDA		Human	PMID:19766732
Biological Process	GO:0046034	ATP metabolic process	AK4	IDA		Human	PMID:19766732
Biological Process	GO:0007420	brain development	Ak4	IEP		Rat	PMID:9813319|RGD:632174
Biological Process	GO:0071456	cellular response to hypoxia	AK4	IMP		Human	PMID:19130895
Biological Process	GO:0071456	cellular response to hypoxia	AK4	IMP		Human	PMID:23474458
Biological Process	GO:0071456	cellular response to hypoxia	AK4	IMP		Human	PMID:26980435
Biological Process	GO:0071456	cellular response to hypoxia	AK4	IMP		Human	PMID:30696468
Biological Process	GO:0046039	GTP metabolic process	AK4	IDA		Human	PMID:19766732
Biological Process	GO:0001889	liver development	Ak4	IEP		Rat	PMID:9813319|RGD:632174
Biological Process	GO:0009142	nucleoside triphosphate biosynthetic process	AK4	IDA		Human	PMID:23416111
Biological Process	GO:2001169	regulation of ATP biosynthetic process	AK4	IMP		Human	PMID:24767988
Biological Process	GO:0002082	regulation of oxidative phosphorylation	AK4	IMP		Human	PMID:26980435
Biological Process	GO:0009410	response to xenobiotic stimulus	Ak4	IEP		Rat	PMID:16538043|RGD:2301096

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern