Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADCY4
  • Mouse genes Adcy4
  • Rat genes Adcy4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adcy4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004016	adenylate cyclase activity	Adcy4	IDA		Rat	PMID:11738086|RGD:2312641
Molecular Function	GO:0004016	adenylate cyclase activity	Adcy4	IDA		Rat	PMID:12711600|RGD:2312674
Molecular Function	GO:0004016	adenylate cyclase activity	Adcy4	IDA		Rat	PMID:1946437|RGD:69739
Molecular Function	GO:0004016	adenylate cyclase activity	Adcy4	IDA		Rat	PMID:8900209|RGD:8554340
Molecular Function	GO:0031683	G-protein beta/gamma-subunit complex binding	Adcy4	IPI	RGD:69319	Rat	PMID:16967511|RGD:1601381
Molecular Function	GO:0005515	protein binding	ADCY4	IPI	UniProtKB:P24588	Human	PMID:17081159
Molecular Function	GO:0005515	protein binding	ADCY4	IPI	UniProtKB:Q02952	Human	PMID:17081159
Molecular Function	GO:0005515	protein binding	ADCY4	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADCY4	IPI	UniProtKB:P37231	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADCY4	IPI	UniProtKB:P62508-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADCY4	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADCY4	IPI	UniProtKB:Q9BV19	Human	PMID:32296183
Molecular Function	GO:0005080	protein kinase C binding	ADCY4	IDA		Human	PMID:17081159
Cellular Component	GO:0005737	cytoplasm	ADCY4	IDA		Human	PMID:11549699
Cellular Component	GO:0030425	dendrite	Adcy4	IDA		Mouse	PMID:9870949
Cellular Component	GO:0005622	intracellular anatomical structure	Adcy4	IDA		Mouse	PMID:9870949
Cellular Component	GO:0016020	membrane	Adcy4	IDA		Rat	PMID:12711600|RGD:2312674
Cellular Component	GO:0016020	membrane	Adcy4	IDA		Rat	PMID:8900209|RGD:8554340
Cellular Component	GO:0005634	nucleus	Adcy4	IDA		Rat	PMID:22899545|RGD:13831348
Cellular Component	GO:0032991	protein-containing complex	Adcy4	IDA		Rat	PMID:16967511|RGD:1601381
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Adcy4	IDA		Mouse	PMID:9870949
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy4	IDA		Rat	PMID:11738086|RGD:2312641
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy4	IDA		Rat	PMID:12711600|RGD:2312674
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy4	IDA		Rat	PMID:8900209|RGD:8554340
Biological Process	GO:0035556	intracellular signal transduction	Adcy4	IDA		Rat	PMID:1946437|RGD:69739

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern