Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADCY3
  • Mouse genes Adcy3
  • Rat genes Adcy3
  • Zfish genes adcy3a,adcy3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adcy3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004016	adenylate cyclase activity	Adcy3	IMP		Mouse	MGI:MGI:1889935|PMID:11055432
Molecular Function	GO:0004016	adenylate cyclase activity	Adcy3	IDA		Rat	PMID:24363043|RGD:10400870
Molecular Function	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity	Adcy3	IDA		Rat	PMID:12711600|RGD:2312674
Molecular Function	GO:0005515	protein binding	Adcy3	IPI	PR:Q6PE84	Mouse	PMID:12122055
Cellular Component	GO:0060170	ciliary membrane	Adcy3	IDA		Mouse	MGI:MGI:5817509|PMID:28053034
Cellular Component	GO:0005929	cilium	Adcy3	IDA		Mouse	MGI:MGI:1889935|PMID:11055432
Cellular Component	GO:0005929	cilium	Adcy3	IDA		Mouse	PMID:22179047
Cellular Component	GO:0005929	cilium	Adcy3	IDA		Mouse	PMID:23077041
Cellular Component	GO:0005929	cilium	Adcy3	IDA		Mouse	PMID:28154160
Cellular Component	GO:0005929	cilium	Adcy3	IDA		Rat	PMID:2255909|RGD:70798
Cellular Component	GO:0005737	cytoplasm	ADCY3	IDA		Human	PMID:11549699
Cellular Component	GO:0005794	Golgi apparatus	Adcy3	IDA		Rat	PMID:15705663|RGD:10400855
Cellular Component	GO:0016020	membrane	ADCY3	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Adcy3	IDA		Mouse	MGI:MGI:1889935|PMID:11055432
Cellular Component	GO:0016020	membrane	Adcy3	IDA		Rat	PMID:12711600|RGD:2312674
Cellular Component	GO:0045121	membrane raft	Adcy3	IDA		Rat	PMID:12748066|RGD:1600980
Cellular Component	GO:0005634	nucleus	Adcy3	IDA		Rat	PMID:11457491|RGD:2312581
Cellular Component	GO:0005886	plasma membrane	ADCY3	IDA		Human	PMID:11549699
Cellular Component	GO:0005886	plasma membrane	Adcy3	IDA		Rat	PMID:12748066|RGD:1600980
Cellular Component	GO:0005886	plasma membrane	Adcy3	IDA		Rat	PMID:12798295|RGD:704368
Cellular Component	GO:0005886	plasma membrane	Adcy3	IDA		Rat	PMID:15705663|RGD:10400855
Biological Process	GO:0007340	acrosome reaction	Adcy3	IMP		Mouse	MGI:MGI:3576427|PMID:15705663
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Adcy3	IMP		Mouse	MGI:MGI:1889935|PMID:11055432
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy3	IMP		Mouse	MGI:MGI:1889935|PMID:11055432
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy3	IDA		Rat	PMID:12711600|RGD:2312674
Biological Process	GO:0006171	cAMP biosynthetic process	Adcy3	IDA		Rat	PMID:24363043|RGD:10400870
Biological Process	GO:1904322	cellular response to forskolin	Adcy3	IMP		Mouse	MGI:MGI:1889935|PMID:11055432
Biological Process	GO:1904322	cellular response to forskolin	Adcy3	IDA		Rat	PMID:24363043|RGD:10400870
Biological Process	GO:0030317	flagellated sperm motility	Adcy3	IMP		Mouse	MGI:MGI:3576427|PMID:15705663
Biological Process	GO:0008355	olfactory learning	Adcy3	IMP		Mouse	MGI:MGI:1889935|PMID:11055432
Biological Process	GO:0007608	sensory perception of smell	Adcy3	IMP		Mouse	MGI:MGI:1889935|PMID:11055432
Biological Process	GO:0007608	sensory perception of smell	Adcy3	IDA		Mouse	PMID:23077041
Biological Process	GO:0007338	single fertilization	Adcy3	IMP		Mouse	MGI:MGI:3576427|PMID:15705663

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern