Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACER3
  • Mouse genes Acer3
  • Rat genes Acer3
  • Zfish genes acer3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acer3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	ACER3	IDA		Human	PMID:30575723
Molecular Function	GO:0071633	dihydroceramidase activity	ACER3	IDA		Human	PMID:20068046
Molecular Function	GO:0071633	dihydroceramidase activity	ACER3	IMP		Human	PMID:20207939
Molecular Function	GO:0017040	N-acylsphingosine amidohydrolase activity	ACER3	IDA		Human	PMID:20068046
Molecular Function	GO:0017040	N-acylsphingosine amidohydrolase activity	ACER3	IMP		Human	PMID:20207939
Molecular Function	GO:0017040	N-acylsphingosine amidohydrolase activity	ACER3	IDA		Human	PMID:30575723
Molecular Function	GO:0070774	phytoceramidase activity	ACER3	IDA		Human	PMID:11356846
Molecular Function	GO:0070774	phytoceramidase activity	ACER3	IDA		Human	PMID:20068046
Molecular Function	GO:0070774	phytoceramidase activity	ACER3	IMP		Human	PMID:26792856
Molecular Function	GO:0070774	phytoceramidase activity	Acer3	IMP		Mouse	MGI:MGI:5749603|PMID:26474409
Molecular Function	GO:0008270	zinc ion binding	ACER3	IDA		Human	PMID:30575723
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ACER3	IDA		Human	PMID:11356846
Cellular Component	GO:0000139	Golgi membrane	ACER3	IDA		Human	PMID:11356846
Cellular Component	GO:0016020	membrane	ACER3	IDA		Human	PMID:30575723
Biological Process	GO:0046514	ceramide catabolic process	ACER3	IMP		Human	PMID:20207939
Biological Process	GO:0046514	ceramide catabolic process	ACER3	IMP		Human	PMID:26792856
Biological Process	GO:0046514	ceramide catabolic process	ACER3	IDA		Human	PMID:30575723
Biological Process	GO:0046514	ceramide catabolic process	Acer3	IMP		Mouse	MGI:MGI:5749603|PMID:26474409
Biological Process	GO:0006954	inflammatory response	Acer3	IMP		Mouse	MGI:MGI:6107569|PMID:26938296
Biological Process	GO:0042552	myelination	ACER3	IMP		Human	PMID:26792856
Biological Process	GO:0071602	phytosphingosine biosynthetic process	ACER3	IDA		Human	PMID:11356846
Biological Process	GO:0071602	phytosphingosine biosynthetic process	ACER3	IDA		Human	PMID:20068046
Biological Process	GO:0008284	positive regulation of cell population proliferation	ACER3	IMP		Human	PMID:20068046
Biological Process	GO:0043067	regulation of programmed cell death	ACER3	IDA		Human	PMID:20068046
Biological Process	GO:0046512	sphingosine biosynthetic process	ACER3	IDA		Human	PMID:20068046
Biological Process	GO:0046512	sphingosine biosynthetic process	ACER3	IMP		Human	PMID:20207939
Biological Process	GO:0046512	sphingosine biosynthetic process	ACER3	IMP		Human	PMID:26792856
Biological Process	GO:0046512	sphingosine biosynthetic process	Acer3	IMP		Mouse	MGI:MGI:5749603|PMID:26474409

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern