Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACAP2
  • Mouse genes Acap2
  • Rat genes Acap2
  • Zfish genes acap2a,acap2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acap2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	ACAP2	IDA		Human	PMID:11062263
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	Acap2	IDA		Mouse	PMID:11001876
Molecular Function	GO:0005515	protein binding	Acap2	IPI	UniProtKB:Q8BGT6	Mouse	MGI:MGI:5516175|PMID:23572513
Molecular Function	GO:0031267	small GTPase binding	Acap2	IPI	UniProtKB:Q6PHN9	Mouse	MGI:MGI:5516175|PMID:23572513
Cellular Component	GO:0010008	endosome membrane	Acap2	IDA		Rat	PMID:23572513|RGD:8554201
Cellular Component	GO:0016020	membrane	ACAP2	HDA		Human	PMID:19946888
Cellular Component	GO:0001726	ruffle	ACAP2	IDA		Human	PMID:11062263
Biological Process	GO:0030029	actin filament-based process	ACAP2	IDA		Human	PMID:11062263
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Acap2	IDA		Rat	PMID:23572513|RGD:8554201
Biological Process	GO:0032456	endocytic recycling	Acap2	IMP		Rat	PMID:23572513|RGD:8554201

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern