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Acap2 Gene Detail
Summary
  • Symbol
    Acap2
  • Name
    ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
  • Synonyms
    9530039J15Rik, Centb2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925868
    NCBI Gene: 78618
  • Gene Overview
    MyGene.info: ACAP2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr16:31092412-31201245 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      108834 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 21.34 cM, cytoband B2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ACAP2, ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ACAP2, ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CENTB2, CNT-B2
  • Links
    NCBI Gene ID: 23527
    neXtProt AC: NX_Q15057
    UniProt: Q15057

  • Chr Location
    3q29; chr3:195274736-195443176 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049076 Ensembl Gene Model | MGI Sequence Detail 108834 C57BL/6J ±  kb
transcript ENSMUST00000231125 Ensembl | MGI Sequence Detail 2334 Not Applicable  
polypeptide ENSMUSP00000154852 Ensembl | MGI Sequence Detail 777 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    623 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 93
    cDNA 92
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65271 Dowler S, et al., Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem J. 2000 Oct 1;351(Pt 1):19-31
  • Latest
    J:245108 Miura Y, et al., ACAP3 regulates neurite outgrowth through its GAP activity specific to Arf6 in mouse hippocampal neurons. Biochem J. 2016 Sep 01;473(17):2591-602

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/17/2018
MGI 6.12
The Jackson Laboratory